Meta AnalysisID 3149

饮用水中锂水平与自杀率关联的系统评价与Meta分析

CRD42018091989

The review will aim to answer the question of what the association is between levels of lithium in public drinking water and the suicidality in the general population.

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Record Fields

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Meta Analysis Id
3149
Evidence Id
11707
Core Evidence Id
11707
Source Meta Analysis Id
3098
Herb2 Meta Analysis Id
HBMA003098
Crd Id
CRD42018091989
Title
Systematic review and meta-analysis of lithium levels in drinking water in association with suicide rates
Review Question
The review will aim to answer the question of what the association is between levels of lithium in public drinking water and the suicidality in the general population.
Study Type Included
All kinds of studies will be included. The exception will be case reports or case series, as well as studies in which there are confounding interventions or agents of which the effect cannot be differentiated from the effect of the lithium alone. The included studies must all include a measure of suicide rates, a measure lithium levels in the drinking water, and demographic data.
Condition Being Studied
Public Mental Health
Participant
Wide range of populations, with no specific exclusion criteria 
Animal
Human Disease Modelled
Intervention
The review will be looking at the effect of lithium levels in drinking water on suicidality.
Comparator Control
Not applicable.
Main Outcome
The main outcome measures of the project will be the lithium levels found in public water supplies, and the association found between these levels and the suicidality in the general population. Different measures have been used to look at the mortality rates: General number of suicide mortalities; a standardized mortality ratio (SMR), calculated by taking into account the sex and age distribution of the population; and mortality rates adjusted for age.
Outcome Measure
Additional Outcome
We will also examine outcomes relating to all-cause mortality (examined using the same methods as primary outcome, should sufficient data be available.)
Study Method
Meta-analysis, Systematic review
Keyword
Drinking Water; Humans; Lithium; Suicide; Water Supply
Contact
Martin Langen [email protected]
Organisational Affiliation
King's College London IoPPN https://www.kcl.ac.uk/ioppn/index.aspx
Funding Source
King's College London
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
England
Review Stage
Review Ongoing
First Submission Date
2018-05-07
Registration Date
2018-05-21
Anticipated Start Date
2017-11-15
Anticipated Completion Date
2018-09-21
Title Cn
饮用水中锂水平与自杀率关联的系统评价与Meta分析
Title En
Systematic review and meta-analysis of lithium levels in drinking water in association with suicide rates
Bilingual Status
complete