Meta AnalysisID 3144

饮用水中锂暴露相关普通人群不良事件:观察性研究系统评价方案

CRD42021290037

There is increasing evidence that trace lithium in the drinking water is associated with lower suicide rates, lower rates of violence and other mental health benefits. Given the benefit, should the trace amounts of lithi

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Record Fields

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Meta Analysis Id
3144
Evidence Id
11702
Core Evidence Id
11702
Source Meta Analysis Id
3093
Herb2 Meta Analysis Id
HBMA003093
Crd Id
CRD42021290037
Title
Adverse events in the general population associated with exposure to lithium in drinking water: Protocol for a systematic review of observational studies
Review Question
There is increasing evidence that trace lithium in the drinking water is associated with lower suicide rates, lower rates of violence and other mental health benefits. Given the benefit, should the trace amounts of lithium be added to drinking water or provided in some other form in the diet? If future policy of adding trace lithium to the drinking water or diet is considered, the possibility of any adverse effects must be ruled out, which leads to the present research question: What adverse events have been observed in the general population from exposure to lithium in drinking water?
Study Type Included
Observational studies including case-control and cohort and other systematic reviews will be included.
Condition Being Studied
Adverse events correlated with increased concentrations of lithium in drinking water.
Participant
Humans with exposure to lithium in drinking water, with no exclusion criteria related to age or sex.
Animal
Human Disease Modelled
Intervention
Lithium in the drinking water.
Comparator Control
Populations not exposed to lithium in the drinking water.
Main Outcome
The main outcome will be adverse events on the population and their association with increasing concentrations of lithium in the drinking water.
Outcome Measure
Additional Outcome
None.
Study Method
Systematic review
Keyword
Drinking Water; Environmental Exposure; Humans; Lithium; Water Pollutants, Chemical
Contact
Gregory Unfried [email protected]
Organisational Affiliation
Indiana University School of Medicine
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
United States of America
Review Stage
Review Ongoing
First Submission Date
2021-11-07
Registration Date
2021-12-08
Anticipated Start Date
2020-08-13
Anticipated Completion Date
2022-11-01
Title Cn
饮用水中锂暴露相关普通人群不良事件:观察性研究系统评价方案
Title En
Adverse events in the general population associated with exposure to lithium in drinking water: Protocol for a systematic review of observational studies
Bilingual Status
complete