Meta AnalysisID 309
非大豆植物蛋白作为功能性成分的健康促进属性：一项人体干预性研究的系统评价
CRD42020181225
Purified protein can be in a form of concentrates (usually above 70% protein on a moisture free basis), isolates (>90%) and hydrolysates. To our knowledge no previous studies systematically reviewed the evidence regar
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Record Fields
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- Meta Analysis Id
- 309
- Evidence Id
- 8867
- Core Evidence Id
- 8867
- Source Meta Analysis Id
- 289
- Herb2 Meta Analysis Id
- HBMA000289
- Crd Id
- CRD42020181225
- Title
- Health promoting attributes of non-soy plant proteins as a functional ingredient: a systematic review of human interventional studies
- Review Question
- Purified protein can be in a form of concentrates (usually above 70% protein on a moisture free basis), isolates (>90%) and hydrolysates. To our knowledge no previous studies systematically reviewed the evidence regarding the effects of selected purified plant protein sources – other than soy - on adult health. The aim of this review was to identify evidence on the effects of purified protein from a wide range of conventional and novel plant sources on glycaemic response, body weight loss, appetite, blood lipids concentration, blood pressure and muscle health.
- Study Type Included
- All searches were limited to interventional, human studies with no restrictions regarding sex, age (>18) or health status. Studies on wholefoods or flours consumed alone, or as a part of a diet will be excluded. Only studies that strictly investigated the effect of purified preparations of plant protein will be considered, in line with the functional ingredient remit. Hence, the interventions included in this review will be limited to: concentrates, isolates and hydrolysates. Studies of genetically modified organisms or plants with altered amino acid profile will not be considered. Studies investigating the effects of medical/prescription food and those referring to weaning food or infant formula will not be included. Reviews, editorials, letters to the editor or other publications not reporting primary research findings were not considered. Only studies published in English language will be reviewed.
- Condition Being Studied
- Postprandial glycemia, insulin response, body weight loss, appetite/satiety, blood lipids concentration, blood pressure and muscle health parameters
- Participant
- Inclusion: Adults (>18 years of age); no restrictions regarding sex or health status Exclusion: Children (< 18 years of age)
- Animal
- Human Disease Modelled
- Intervention
- Intake of dietary proteins from the following sources: pea, chickpea, lentil, lupin, faba bean, hemp, sunflower, pumpkin, oat, rice, rapeseed, buckwheat, quinoa, duckweed, alfalfa, potato, sacha inchi, mushrooms. Only concentrated forms will be considered (concentrates, isolates or hydrolysates).
- Comparator Control
- Other protein source (animal- or plant-based), placebo/control (e.g. water, maltodextrin, other foods with manipulated macronutrient content) or receiving another intervention.
- Main Outcome
- Change in glycemic response and appetite (glucose; insulin; glucagon; GLP-1; CCK; subjective appetite, satiety, hunger, fullness; ad libitum food intake), blood lipid concentration (total cholesterol; LDL, HDL, triglicerides); blood pressure; muscle health (thickness; mass; strength), body weight (weight loss/gain in kg; BMI) from baseline to the last available follow-up. Measures of effect Where studies used the same type of intervention and comparator we will provide summaries of intervention effects for each study by calculating risk ratios (for dichotomous outcomes) or standardised mean differences (for continuous outcomes).
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not applicable
- Study Method
- Narrative synthesis, Systematic review
- Keyword
- Health Promotion; Humans; Plant Proteins; Research Design
- Contact
- Marta Lonnie [email protected]
- Organisational Affiliation
- Rowett Institute, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, United Kingdom https://www.abdn.ac.uk/rowett/
- Funding Source
- Tate & Lyle PLC, 1 Kingsway, London, WC2B 6AT, United Kingdom Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> Project code: A16920 / TL 4500024884
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Scotland
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-04-20
- Registration Date
- 2020-05-20
- Anticipated Start Date
- 2020-03-13
- Anticipated Completion Date
- 2020-05-31
- Title Cn
- 非大豆植物蛋白作为功能性成分的健康促进属性：一项人体干预性研究的系统评价
- Title En
- Health promoting attributes of non-soy plant proteins as a functional ingredient: a systematic review of human interventional studies
- Bilingual Status
- complete