Meta AnalysisID 2986
重症COVID-19患者乳糖脱氢酶的Meta分析：回顾性研究
CRD42020178960
We will perform an analysis of the current scientific literature to investigate whether lactose dehydrogenase (LAC) may play a role in distinguishing the presence of severe COVID-19 in patients with viral infection and w
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2986
- Evidence Id
- 11544
- Core Evidence Id
- 11544
- Source Meta Analysis Id
- 2936
- Herb2 Meta Analysis Id
- HBMA002936
- Crd Id
- CRD42020178960
- Title
- Lactose dehydrogenase in patients with severe COVID-19: a meta-analysis of retrospective study
- Review Question
- We will perform an analysis of the current scientific literature to investigate whether lactose dehydrogenase (LAC) may play a role in distinguishing the presence of severe COVID-19 in patients with viral infection and whether its value changes substantially in patients with viral infection.
- Study Type Included
- Included: randomized controlled trials, case-control study, cohort study, cross-sectional studies, case reports, etc. Second, studies in which the clinical characteristics of patients with COVID-19 infection (age, regions) were included.
- Condition Being Studied
- Coronavirus disease 2019 (COVID-19) is a human infectious disease caused by coronavirus. COVID-19 is a new infectious disease in the world, whose origin, pathological mechanism and treatment strategy are not fully understood. In the course of disease development and treatment, laboratory examination is very important to monitor the change of the disease and evaluate the therapeutic effect.
- Participant
- Patients with confirmed COVID-19 infection.
- Animal
- Human Disease Modelled
- Intervention
- This review is looking at the relationship between the Lactose dehydrogenase and severe coronavirus disease 2019 (COVID-19) infections.
- Comparator Control
- No control.
- Main Outcome
- Lactose dehydrogenase function in relation to severe COVID-19 infection. Measures of effect The units of measurement in each result were standardized. The weighted mean differences (WMDs) and corresponding 95% confidence intervals (CIs) were calculated by random effects models and fixed-effect models.
- Outcome Measure
- Additional Outcome
- Relationship between myocardial enzyme function and severe COVID-19 infection. Measures of effect The units of measurement in each result were standardized. The weighted mean differences (WMDs) and corresponding 95% confidence intervals (CIs) were calculated by random effects models and fixed-effect models.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- COVID-19; Humans; Lactose; Lactose Intolerance; Oxidoreductases; Personality; Retrospective Studies; severe acute respiratory syndrome coronavirus 2
- Contact
- Xiaoyi Huang [email protected]
- Organisational Affiliation
- School of Nursing, Guangdong Pharmaceutical University, 283 Jianghai Avenue, Haizhu District, Guangzhou, China
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-04-11
- Registration Date
- 2020-04-17
- Anticipated Start Date
- 2019-12-01
- Anticipated Completion Date
- 2020-05-10
- Title Cn
- 重症COVID-19患者乳糖脱氢酶的Meta分析：回顾性研究
- Title En
- Lactose dehydrogenase in patients with severe COVID-19: a meta-analysis of retrospective study
- Bilingual Status
- complete