Meta AnalysisID 2948
大豆食品和大豆异黄酮摄入与心血管疾病：一项前瞻性队列研究的Meta分析
CRD42020190070
The primary aim of this study is to investigate the association between soy food intake and risk of cardiovascular disease (total cardiovascular disease, stroke, coronary heart disease). The associations for specific soy
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2948
- Evidence Id
- 11506
- Core Evidence Id
- 11506
- Source Meta Analysis Id
- 2898
- Herb2 Meta Analysis Id
- HBMA002898
- Crd Id
- CRD42020190070
- Title
- Consumptions of soy foods and soy isoflavones in relation to cardiovascular disease: a meta-analysis of prospective cohort studies
- Review Question
- The primary aim of this study is to investigate the association between soy food intake and risk of cardiovascular disease (total cardiovascular disease, stroke, coronary heart disease). The associations for specific soy foods, including tofu, natto, miso, will also be examined. A dose-response meta-analysis for soy isoflavone intake is planned.
- Study Type Included
- Only prospective cohort studies will be included in the meta-analysis.
- Condition Being Studied
- The outcome investigated will be risk of cardiovascular disease, considering either non-fatal or fatal events. Cardiovascular outcomes will include total cardiovascular disease, coronary heart disease, and stroke.
- Participant
- Inclusion criterion will be consideration of studies conducted on the general adult population free of cardiovascular disease at baseline.
- Animal
- Human Disease Modelled
- Intervention
- Inclusion criterion will be studies considering the exposure to the following: total soy foods, soy protein, tofu, natto, miso, soy isoflavones.
- Comparator Control
- Risk assessment will be conducted comparing exposure to lowest intakes.
- Main Outcome
- The outcome investigated will be risk of cardiovascular disease, considering either non-fatal or fatal events. Cardiovascular outcomes will include total cardiovascular disease, coronary heart disease, and stroke. The outcomes of the studies included are generally assessed through (i) direct interview, (ii) link with disease registries records, (iii) link with hospital admission records, and (iv) link with death registries. Measures of effect The effect measure for the main outcome is relative risk.
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not applicable
- Study Method
- Epidemiologic, Meta-analysis, Prevention, Systematic review
- Keyword
- Cardiovascular Diseases; Diet; Humans; Isoflavones; Prospective Studies; Soy Foods
- Contact
- Jia-Yi Dong [email protected]
- Organisational Affiliation
- Osaka University
- Funding Source
- This study was supported by Japan Society for the Promotion of Science KAKENHI. Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> A18H063910 and T19K214700
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Japan
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-06-03
- Registration Date
- 2020-07-05
- Anticipated Start Date
- 2020-06-17
- Anticipated Completion Date
- 2020-08-15
- Title Cn
- 大豆食品和大豆异黄酮摄入与心血管疾病：一项前瞻性队列研究的Meta分析
- Title En
- Consumptions of soy foods and soy isoflavones in relation to cardiovascular disease: a meta-analysis of prospective cohort studies
- Bilingual Status
- complete