Meta AnalysisID 2945
大豆异黄酮摄入对骨密度的影响：一项双盲随机对照试验的系统评价与Meta分析
CRD42023387159
Does soy/isoflavones or phytoestrogen intake have e significant effect on Bone Mineral Density to improve postmenopausal-related quality of life?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2945
- Evidence Id
- 11503
- Core Evidence Id
- 11503
- Source Meta Analysis Id
- 2888
- Herb2 Meta Analysis Id
- HBMA002888
- Crd Id
- CRD42023387159
- Title
- The effect of soy isoflavone intake on bone mineral density: A systematic review and meta-analysis of double-blind randomized control trial
- Review Question
- Does soy/isoflavones or phytoestrogen intake have e significant effect on Bone Mineral Density to improve postmenopausal-related quality of life?
- Study Type Included
- RCT
- Condition Being Studied
- Several animal studies have provided convincing data on the significant improvement of bone mass after soy protein or isolated isoflavone-enriched soy extract supplementation (Alekel et al., 2010). Soy isoflavones have been proposed as alternatives to hormone therapy (HT) for preventing bone loss (William W Wong et al., 2009), and a high intake of dietary isoflavones are associated with an increase in bone mineral content in postmenopausal women
- Participant
- Womens
- Animal
- Human Disease Modelled
- Intervention
- Soy isoflavone intakes
- Comparator Control
- Control of placebo intake
- Main Outcome
- Bone mineral density Measures of effect relative risk and odd ratio
- Outcome Measure
- Additional Outcome
- Bone strength
- Study Method
- Intervention, Systematic review
- Keyword
- Humans; Isoflavones; Minerals; Phytoestrogens; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic
- Contact
- Teshome Bekele Elema [email protected]
- Organisational Affiliation
- Addis Ababa University www.aau.edu.et
- Funding Source
- Not applicable Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> NA
- Other Selection Criteria
- Final Publication
- Same Topic Review
- From the meta-analysis of the isoflavone effect on bone resorption, the researcher found that menopausal and postmenopausal women lose a mean of 2–5% and up to 3% in a year respectively because of estrogen dysregulation and deficiency (Lambert, Hu, & Jeppesen, 2017).
- Published Protocol
- Review Type
- Language
- English
- Country
- Ethiopia
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-12-22
- Registration Date
- 2023-01-02
- Anticipated Start Date
- 2021-10-13
- Anticipated Completion Date
- 2023-01-24
- Title Cn
- 大豆异黄酮摄入对骨密度的影响：一项双盲随机对照试验的系统评价与Meta分析
- Title En
- The effect of soy isoflavone intake on bone mineral density: A systematic review and meta-analysis of double-blind randomized control trial
- Bilingual Status
- complete