Meta AnalysisID 2941

大豆异黄酮摄入及素食饮食与乳腺癌发病风险:一项前瞻性研究的Meta分析

CRD42022325222

What is the evidence from prospective cohort studies for an association between intake of isoflavones from soy products or following a vegetarian or pescetarian diet and risk of breast cancer

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Record Fields

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Meta Analysis Id
2941
Evidence Id
11499
Core Evidence Id
11499
Source Meta Analysis Id
2884
Herb2 Meta Analysis Id
HBMA002884
Crd Id
CRD42022325222
Title
Soy isoflavone intake and vegetarianism in relation to risk of breast cancer: a meta-analysis of prospective studies
Review Question
What is the evidence from prospective cohort studies for an association between intake of isoflavones from soy products or following a vegetarian or pescetarian diet and risk of breast cancer
Study Type Included
Only peer-reviewed prospective cohort studies will be included. Cross-sectional studies, case-control studies, ecological studies, case-reports, reviews, randomised controlled trials, qualitative studies, and commentaries, as well as unpublished literature will be excluded.
Condition Being Studied
Incident (fatal/non-fatal) breast cancer determined from cancer registries, death records, physician records, hospital records, or self-report
Participant
Women aged 18 years or older, excluding women with any cancer diagnosis at baseline.
Animal
Human Disease Modelled
Intervention
Soy isoflavone intake (mg/day) Diet group: following a vegetarian (including vegan) or pescatarian diet.
Comparator Control
Low or lowest soy isoflavone intake (mg/day) in comparison to high soy isoflavone intakeDiet group: Meat-eaters (non-vegetarians) in comparison to pescatarians or vegetarians
Main Outcome
Breast cancer Measures of effect Risk estimates including relative risk or hazard ratios.
Outcome Measure
Additional Outcome
Incident postmenopausal breast cancer, premenopausal breast cancer, oestrogen receptor positive breast cancer, oestrogen receptor negative breast cancer. Measures of effect Risk estimates specifically relative risk or hazard ratios
Study Method
Epidemiologic, Meta-analysis, Systematic review
Keyword
Breast Neoplasms; Diet, Vegetarian; Female; Humans; Isoflavones; Prospective Studies; Vegetarians
Contact
Cody Watling [email protected]
Organisational Affiliation
Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford https://www.ceu.ox.ac.uk/
Funding Source
Dr. Watling was supported by the Nuffield Department of Population Health Doctoral Scholarship Dr. Key is supported by Cancer Research UK (C8221/A29017) and Wellcome Trust (205212/Z/16/Z) Dr Perez-Cornago is supported by a Cancer Research UK Population Research Fellowship (C60192/A28516) (London, UK) and by the World Cancer Research Fund (WCRF UK) (London, UK), as part of the World Cancer Research Fund International grant programme (2019/1953) Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> C8221/A29017 205212/Z/16/ZC60192/A28516 2019/1953
Other Selection Criteria
Final Publication
Same Topic Review
Not applicable
Published Protocol
Review Type
Language
English
Country
England
Review Stage
Review Ongoing
First Submission Date
2022-12-20
Registration Date
2022-12-21
Anticipated Start Date
2023-01-01
Anticipated Completion Date
2023-02-28
Title Cn
大豆异黄酮摄入及素食饮食与乳腺癌发病风险:一项前瞻性研究的Meta分析
Title En
Soy isoflavone intake and vegetarianism in relation to risk of breast cancer: a meta-analysis of prospective studies
Bilingual Status
complete