Meta AnalysisID 2935

急诊科异丙醇鼻腔吸入治疗恶心:一项系统评价与Meta分析

CRD42022299815

Among adult patients presenting to the emergency department with nausea and vomiting, does inhalation of isopropyl alcohol compared to usual care or placebo result in improvement in the severity of nausea and number of v

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Record Fields

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Meta Analysis Id
2935
Evidence Id
11493
Core Evidence Id
11493
Source Meta Analysis Id
2879
Herb2 Meta Analysis Id
HBMA002879
Crd Id
CRD42022299815
Title
Isopropyl Alcohol Nasal Inhalation for Nausea in the Emergency Department: A Systematic Review and Meta-Analysis
Review Question
Among adult patients presenting to the emergency department with nausea and vomiting, does inhalation of isopropyl alcohol compared to usual care or placebo result in improvement in the severity of nausea and number of vomiting episodes?
Study Type Included
Randomized controlled trials
Condition Being Studied
Emergency department presentations with a chief complaint of nausea and vomiting
Participant
Adult patients (18+) presenting to the emergency department with nausea and vomiting
Animal
Human Disease Modelled
Intervention
Intervention: Inhalation of isopropyl alcohol from a commercially prepared medical preparation pad saturated with isopropyl alcohol.
Comparator Control
Comparison: Usual care (any anti-emetic drug or therapy) or placebo
Main Outcome
Severity of nausea post inhalation treatment as measured by validated scale or medical or nursing observation. Scales will be transformed to a score between 0 and 100, where 0 is complete resolution of nausea, and a minimum clinically significant difference from baseline defined as 15 mm on the visual analog scale for nausea published by Hendey et al.
Outcome Measure
Additional Outcome
Number of vomiting episodes as measured by patient report, or medical or nursing observation.
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
2-Propanol; Antiemetics; Emergency Service, Hospital; Humans; Nausea; Ondansetron
Contact
Stefanie Lee [email protected]
Organisational Affiliation
McMaster University
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Canada
Review Stage
Review Ongoing
First Submission Date
2021-12-21
Registration Date
2022-01-21
Anticipated Start Date
2021-09-16
Anticipated Completion Date
2022-02-28
Title Cn
急诊科异丙醇鼻腔吸入治疗恶心:一项系统评价与Meta分析
Title En
Isopropyl Alcohol Nasal Inhalation for Nausea in the Emergency Department: A Systematic Review and Meta-Analysis
Bilingual Status
complete