Meta AnalysisID 2934

异丙醇吸入对比5-HT3拮抗剂治疗恶心:一项随机对照试验的Meta分析

CRD42021259620

What is the effectiveness of inhaled isopropyl alcohol compared with 5-hydroxytriptamine-3 (5-HT3) antagonists for the treatment of nausea in any clinical setting?

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Record Fields

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Meta Analysis Id
2934
Evidence Id
11492
Core Evidence Id
11492
Source Meta Analysis Id
2878
Herb2 Meta Analysis Id
HBMA002878
Crd Id
CRD42021259620
Title
Isopropyl alcohol inhalation versus 5-HT3 antagonists for treatment of nausea: a meta-analysis of randomised controlled trials
Review Question
What is the effectiveness of inhaled isopropyl alcohol compared with 5-hydroxytriptamine-3 (5-HT3) antagonists for the treatment of nausea in any clinical setting?
Study Type Included
Prospective randomised trials comparing the effectiveness of inhaled isopropyl alcohol with that of 5-HT3 antagonists for the treatment of nausea
Condition Being Studied
Nausea
Participant
Patients of all ages experiencing nausea in a medial or surgical setting
Animal
Human Disease Modelled
Intervention
Inhaled isopropyl alcohol
Comparator Control
5-HT3 antagonists
Main Outcome
Numerical measures of sensation of nausea -severity of nausea or vomiting, or both, after treatment as measured by a validated scale -duration of nausea or vomiting, or both, after treatment as measured by a validated scale Measures of effect -patient reported effects, including but not limited to: Visual Analogue Scale (VAS), Descriptive Ordinal Scales (DOS) and Verbal Numerical Rating Scales (VNRS). -Risk ratios, standard mean differences.
Outcome Measure
Additional Outcome
• Any adverse effects • Use of additional pharmacological anti-emetics • Patient satisfaction measured by a validated scale Measures of effect Risk ratios, standard mean differences.
Study Method
Meta-analysis, Systematic review
Keyword
2-Propanol; Antiemetics; Humans; Nausea; Serotonin 5-HT3 Receptor Antagonists
Contact
James Kimber [email protected]
Organisational Affiliation
University of Adelaide
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Australia
Review Stage
Review Ongoing
First Submission Date
2021-06-11
Registration Date
2021-07-11
Anticipated Start Date
2021-06-28
Anticipated Completion Date
2022-01-01
Title Cn
异丙醇吸入对比5-HT3拮抗剂治疗恶心:一项随机对照试验的Meta分析
Title En
Isopropyl alcohol inhalation versus 5-HT3 antagonists for treatment of nausea: a meta-analysis of randomised controlled trials
Bilingual Status
complete