Meta AnalysisID 2843

菊粉对血脂谱的影响:随机临床试验的系统评价和Meta分析

CRD42022354480

Is inulin effective supplementation on lipid profile among adults?

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Record Fields

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Meta Analysis Id
2843
Evidence Id
11401
Core Evidence Id
11401
Source Meta Analysis Id
2785
Herb2 Meta Analysis Id
HBMA002785
Crd Id
CRD42022354480
Title
The effect of Inulin on lipid profile: A systematic review and meta‐analysis of randomized clinical trials
Review Question
Is inulin effective supplementation on lipid profile among adults?
Study Type Included
Randomized controlled trials (RCTs)
Condition Being Studied
The most common strategies for the prevention or reversal of obesity, and many associated blood lipid disorders, are dietary control or manipulation and physical activity. However, in recent years, the interest in the utility of conjunctive or alternative therapies has proliferated. Moreover, the epidemiological data in some relevant studies suggest an association between lipid profile and inulin supplementation. Inulin, mainly composed of inulin, fructooligosaccharides (FOS) and galactooligosaccharides (GOS), is a class of linear fructans that is connected with β (2-1) bonds and is often defined as one kind of prebiotic. Many studies have provided evidence that inulin has many health benefits, such as improving immune function, lowering blood pressure, and improving blood lipids if taken at a moderate dose. Although a growing body of human clinical trials, including randomized controlled trials, support that inulin intake plays an important role in lipid profile, the results have remained controversial.
Participant
Adult subjects (18 years and older)
Animal
Human Disease Modelled
Intervention
Inulin
Comparator Control
Placebo/control
Main Outcome
Lipid profile (TC, TG, HDL, and LDL) Measures of effect TC, TG, HDL, and LDL
Outcome Measure
Additional Outcome
Apolipoprotein A
Study Method
Meta-analysis, Systematic review
Keyword
Dietary Supplements; Humans; Inulin; Randomized Controlled Trials as Topic; Triglycerides
Contact
Mahdi vajdi [email protected]
Organisational Affiliation
Tabriz University of Medical Sciences, Tabriz, Iran
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Iran
Review Stage
Review Ongoing
First Submission Date
2022-08-18
Registration Date
2022-08-29
Anticipated Start Date
2022-08-31
Anticipated Completion Date
2022-11-30
Title Cn
菊粉对血脂谱的影响:随机临床试验的系统评价和Meta分析
Title En
The effect of Inulin on lipid profile: A systematic review and meta‐analysis of randomized clinical trials
Bilingual Status
complete