Meta AnalysisID 2839
菊苣来源的菊粉型果聚糖补充剂在血压管理中的作用：随机对照试验的系统评价、Meta分析和Meta回归
CRD42020200748
To evaluate the effect of chicory-derived inulin-type fructans (ITF) supplementation in blood pressure management in humans irrespective of the health status, in comparison with placebo/control.
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2839
- Evidence Id
- 11397
- Core Evidence Id
- 11397
- Source Meta Analysis Id
- 2782
- Herb2 Meta Analysis Id
- HBMA002782
- Crd Id
- CRD42020200748
- Title
- Effects of chicory-derived inulin-type fructans (ITF) supplementation in blood pressure management: systematic review, meta-analysis and meta-regression of randomized controlled trials.
- Review Question
- To evaluate the effect of chicory-derived inulin-type fructans (ITF) supplementation in blood pressure management in humans irrespective of the health status, in comparison with placebo/control.
- Study Type Included
- Randomized clinical trial will be included in this systematic review and meta-analysis.
- Condition Being Studied
- Blood pressure management in adults.
- Participant
- Adult population will be included in this systematic review and meta-analysis. We will limit this systematic review and meta-analysis to trials / clinical studies performed only in humans.
- Animal
- Human Disease Modelled
- Intervention
- Chicory inulin-type fructans (ITF) irrespective of their degree polymerization (DP) chain length (e.g. oligofructose, inulin, mixed of oligofructose and inulin). Exclusions: • Trials / clinical studies only evaluating inulin-type fructans (ITF) obtained from other sources than chicory root (e.g. agave, artichokes, yacon) will be excluded. • Trials / clinical studies using chicory inulin-type fructans (ITF) mixed with probiotics (synbiotics) will be excluded. • Trials / clinical studies using modified inulin with other active compounds (e.g. inulin propionate-esters) will be excluded.
- Comparator Control
- Placebo/control (e.g. maltodextrin, sucrose, dextrose, cellulose, starch, control meal without chicory ITF). Exclusions: • Trials / clinical studies only evaluating chicory inulin-type fructans (ITF) without using any placebo or comparable control will be excluded. • Trials / clinical studies comparing chicory inulin-type fructans (ITF) as prebiotics with probiotics without using any appropriate placebo/control will be excluded.
- Main Outcome
- Blood pressures (sytolic blood pressure/SBP and diastolic blood pressure/DBP) which are relevant for health claim submission as outlined by European Food Safety Agency (EFSA) in the ‘Guidance for the scientic requirements for health claims related to antioxidants, oxidative damage and cardiovascular health’ will be evaluated. For that, trials / clinical studies that report either SBP or DBP or both will be eligible for inclusion. Measures of effect The overall effect size mean difference (MD) will be synthesized from differences of changes from baseline and its respective standard deviation between chicory-derived ITF supplementation and placebo/control.
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not applicable
- Study Method
- Meta-analysis, Systematic review, Other
- Keyword
- Blood Pressure; Chicory; Dietary Supplements; Fructans; Humans; Inulin; Randomized Controlled Trials as Topic
- Contact
- Dr. Yoghatama Cindya Zanzer [email protected]
- Organisational Affiliation
- BENEO GmbH, CRDS-Nutrition Science, Germany www.beneo.com
- Funding Source
- Funding is provided by BENEO GmbH Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span>
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Germany
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-07-28
- Registration Date
- 2020-08-28
- Anticipated Start Date
- 2020-08-28
- Anticipated Completion Date
- 2020-12-15
- Title Cn
- 菊苣来源的菊粉型果聚糖补充剂在血压管理中的作用：随机对照试验的系统评价、Meta分析和Meta回归
- Title En
- Effects of chicory-derived inulin-type fructans (ITF) supplementation in blood pressure management: systematic review, meta-analysis and meta-regression of randomized controlled trials.
- Bilingual Status
- complete