Meta AnalysisID 2837
菊苣菊粉型果聚糖补充剂在体重管理中的应用：随机对照试验的系统评价、Meta分析和Meta回归
CRD42020184908
To examine the effect of chicory inulin-type fructans (ITF) supplementation in component of weight management in humans irrespective of the health status, in comparison with placebo/control.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2837
- Evidence Id
- 11395
- Core Evidence Id
- 11395
- Source Meta Analysis Id
- 2780
- Herb2 Meta Analysis Id
- HBMA002780
- Crd Id
- CRD42020184908
- Title
- Chicory inulin-type fructans supplementation in weight management: systematic review, meta-analysis and meta-regression of randomized controlled trials.
- Review Question
- To examine the effect of chicory inulin-type fructans (ITF) supplementation in component of weight management in humans irrespective of the health status, in comparison with placebo/control.
- Study Type Included
- Randomized clinical trial will be included in this systematic review and meta-analysis.
- Condition Being Studied
- Weight management in adults.
- Participant
- Adult population will be included in this systematic review and meta-analysis. We will limit this systematic review and meta-analysis to trials / clinical studies performed only in humans. <u>Exclusions:</u> • Trials / clinical studies evaluating chicory inulin-type fructans (ITF) in children and adolescents will be excluded.
- Animal
- Human Disease Modelled
- Intervention
- Chicory inulin-type fructans (ITF) irrespective of their degree polymerization (DP) chain length (e.g. oligofructose, inulin, mixed of oligofructose and inulin). <u>Exclusions:</u> • Trials / clinical studies only evaluating inulin-type fructans (ITF) obtained from other sources than chicory root (e.g. agave, artichokes, yacon) will be excluded. • Trials / clinical studies using chicory inulin-type fructans (ITF) mixed with probiotics (synbiotics) will be excluded. • Trials / clinical studies using modified inulin with other active compounds (e.g. inulin propionate-esters) will be excluded.
- Comparator Control
- Placebo/control (e.g. maltodextrin, sucrose, dextrose, cellulose, starch, control meal without chicory ITF). <u>Exclusions:</u> • Trials / clinical studies only evaluating chicory inulin-type fructans (ITF) without using any placebo or comparable control will be excluded. • Trials / clinical studies comparing chicory inulin-type fructans (ITF) as prebiotics with probiotics without using any appropriate placebo/control will be excluded
- Main Outcome
- Five aspects of weight management (body weight, BMI, total body fat, body fat percentage, and waist circumference) which are relevant for health claim submission as outlined by European Food Safety Agency (EFSA) in the ‘Guidance on the scientific requirements for health claims related to appetite ratings, weight management, and blood glucose concentrations’ will be evaluated. For that, trials / clinical studies that report one or more aspect of weight management will be eligible for inclusion. Measures of effect The overall effect size mean difference (MD) will be synthesized from differences of changes from baseline and its respective standard deviation between chicory-derived ITF supplementation and placebo/control.
- Outcome Measure
- Additional Outcome
- Not applicable Measures of effect Not applicable
- Study Method
- Meta-analysis, Systematic review, Other
- Keyword
- Chicory; Dietary Supplements; Fructans; Humans; Inulin; Nutrition Therapy
- Contact
- Dr. Yoghatama Cindya Zanzer [email protected]
- Organisational Affiliation
- BENEO GmbH, CRDS-Nutrition Science, Germany www.beneo.com
- Funding Source
- Funding provided by BENEO GmbH Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span>
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Germany
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-05-27
- Registration Date
- 2020-07-05
- Anticipated Start Date
- 2020-05-01
- Anticipated Completion Date
- 2020-08-31
- Title Cn
- 菊苣菊粉型果聚糖补充剂在体重管理中的应用：随机对照试验的系统评价、Meta分析和Meta回归
- Title En
- Chicory inulin-type fructans supplementation in weight management: systematic review, meta-analysis and meta-regression of randomized controlled trials.
- Bilingual Status
- complete