Meta AnalysisID 2836
菊苣来源的菊粉型果聚糖对微生物群组成和肠道功能的影响
CRD42020162892
What are the effects of chicory-derived inulin-type fructans have on Bifidobacteria spp. abundance and gut microbiota composition as well as gastrointestinal function (including bowel movement frequency and stool consist
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Record Fields
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- Meta Analysis Id
- 2836
- Evidence Id
- 11394
- Core Evidence Id
- 11394
- Source Meta Analysis Id
- 2779
- Herb2 Meta Analysis Id
- HBMA002779
- Crd Id
- CRD42020162892
- Title
- Effects of inulin type fructans from chicory on microbiota composition and bowel function
- Review Question
- What are the effects of chicory-derived inulin-type fructans have on Bifidobacteria spp. abundance and gut microbiota composition as well as gastrointestinal function (including bowel movement frequency and stool consistency)?
- Study Type Included
- We will include randomised controlled trials (RCTs).
- Condition Being Studied
- Gastrointestinal health.
- Participant
- Humans of all age groups and all health conditions will be included.
- Animal
- Human Disease Modelled
- Intervention
- Inulin-type fructans (including native inulin, oligofructose or inulin HP) either alone or in combination, provided either in diets/ specific foods or as dietary supplements. We will consider RCTs in which the intervention had a minimum duration of seven days.
- Comparator Control
- • Usual diet • No intervention • Placebo • Another chicory-derived inulin-type fructan • Another type of prebiotic fiber • Another type of dietary fiber Concomitant interventions will have to be the same in both the intervention and comparator groups to allow fair comparisons and to isolate the effect of inulin-type fructans on health outcomes
- Main Outcome
- Primary outcome: • Abundance of Bifidobacterium spp. Measures of effect We will consider outcomes measured after a minimum follow‐up of seven days.
- Outcome Measure
- Additional Outcome
- Secondary outcomes: • Health‐related quality of life. • Stool frequency • Stool consistency • Abdominal symptoms (including pain or discomfort) • Abundance of Lactobacillus spp. • Abundance of other bacteria or bacteria groups • Adverse events We will include trials reporting at least on the primary outcome measure in the publication. Measures of effect With the exception of adverse events (measured at any time after participants were randomised to intervention/comparator groups) we will consider outcomes measured after a minimum follow-up of seven days.
- Study Method
- Intervention, Systematic review
- Keyword
- Humans
- Contact
- Szimonetta Lohner [email protected]
- Organisational Affiliation
- Department of Paediatrics, Clinical Center of the University of Pécs, Medical School, University of Pécs, Pécs, Hungary.
- Funding Source
- Funding provided by Beneo GmbH, Mannheim, Germany.
- Other Selection Criteria
- Final Publication
- Nagy DU, Sándor-Bajusz KA, Bódy B, Decsi T, Van Harsselaar J, Theis S, Lohner S. Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses. Crit Rev Food Sci Nutr. 2022 Jul 14:1-18. doi: 10.1080/10408398.2022.2098246. https://www.tandfonline.com/doi/abs/10.1080/10408398.2022.2098246?journalCode=bfsn20
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Germany, Hungary
- Review Stage
- Review Completed published
- First Submission Date
- 2020-01-24
- Registration Date
- 2020-04-28
- Anticipated Start Date
- 2020-01-15
- Anticipated Completion Date
- 2020-12-31
- Title Cn
- 菊苣来源的菊粉型果聚糖对微生物群组成和肠道功能的影响
- Title En
- Effects of inulin type fructans from chicory on microbiota composition and bowel function
- Bilingual Status
- complete