Meta AnalysisID 2825

乳酸林格液联合吲哚美辛预防ERCP术后胰腺炎

CRD42018112698

Studies have shown that indometachin is effective in the prevention of post-ERCP (post-endoscopic retrograde cholangeopancreatography) pancreatitis. They have also shown that perfusion is beneficial, and that lactated Ri

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Record Fields

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Meta Analysis Id
2825
Evidence Id
11383
Core Evidence Id
11383
Source Meta Analysis Id
2768
Herb2 Meta Analysis Id
HBMA002768
Crd Id
CRD42018112698
Title
Lactated Ringer's in combination with indomethacin for the prevention of post-ERCP pancreatitis
Review Question
Studies have shown that indometachin is effective in the prevention of post-ERCP (post-endoscopic retrograde cholangeopancreatography) pancreatitis. They have also shown that perfusion is beneficial, and that lactated Ringer's is more effective that normal saline. Review questions: Is a combination of these interventions even more beneficial? Is one of them superior to the other?
Study Type Included
RCTs.
Condition Being Studied
Studies have shown that indometachin is effective in the prevention of post-ERCP pancreatitis. They have also shown that perfusion is beneficial, and that lactated Ringer is more effective that normal saline. In this review, we therefore aim to determine whether a combination of these interventions is even more beneficial, and whether one is superior to the other? A systematic review on this question has never been carried out before.
Participant
Inclusion: patients undergoing ERCP examinations, aged over 18 years. Exclusion: none.
Animal
Human Disease Modelled
Intervention
Indomethacin alone, LR infusion alone, a combination of these.
Comparator Control
Indomethacin alone, LR infusion alone, a combination of these.
Main Outcome
Rate of pancreatitis, severity of pancreatitis.
Outcome Measure
Additional Outcome
None.
Study Method
Intervention, Network meta-analysis, Prevention, Systematic review
Keyword
Body Fluids; Cholangiopancreatography, Endoscopic Retrograde; Drug Therapy; Humans; Indomethacin; Isotonic Solutions; Pancreatitis; Postoperative Care; Postoperative Complications; Postoperative Period; Treatment Outcome
Contact
Katalin Marta [email protected]
Organisational Affiliation
Institute for Translational Medicine, University of Pécs, Medical School
Funding Source
Institute for Translational Medicine, UNKP-18-3-I New National Excellence Program of the Ministry of Human Capacities
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Hungary
Review Stage
Review Ongoing
First Submission Date
2018-10-15
Registration Date
2018-12-06
Anticipated Start Date
2018-10-12
Anticipated Completion Date
2019-02-28
Title Cn
乳酸林格液联合吲哚美辛预防ERCP术后胰腺炎
Title En
Lactated Ringer's in combination with indomethacin for the prevention of post-ERCP pancreatitis
Bilingual Status
complete