Meta AnalysisID 2799

东莨菪碱-异丙嗪对产程持续时间的效果:临床试验的系统评价与Meta分析

CRD42021272783

Is promethazine effective in reducing labor duration? Does hyoscine have an effect on reducing labor duration? Using promethazine and hyoscine to shorten labor is effective? In reducing labor duration, do promethazine an

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Record Fields

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Meta Analysis Id
2799
Evidence Id
11357
Core Evidence Id
11357
Source Meta Analysis Id
2744
Herb2 Meta Analysis Id
HBMA002744
Crd Id
CRD42021272783
Title
The effectiveness of Hyoscine-promethazine on labor duration: a systematic review and meta-analysis of clinical trials
Review Question
Is promethazine effective in reducing labor duration? Does hyoscine have an effect on reducing labor duration? Using promethazine and hyoscine to shorten labor is effective? In reducing labor duration, do promethazine and hyoscine differ in their effectiveness?
Study Type Included
Each type of RCT (Randomized Controlled Trial, Randomized Placebo-controlled Trial, Randomized double-blind controlled trial, Pilot Randomized Trial) will be included in this systematic review and meta-analysis.
Condition Being Studied
Efficacy of Promethazine and Hyoscine in reducing the duration of labor
Participant
Pregnant women who received promethazine or/and hyoscine in the labor
Animal
Human Disease Modelled
Intervention
Perscription of Promethazine or/and Hyoscine in the labor
Comparator Control
Pregnant women who not received promethazine or/and hyoscine in the labor (They may receive Normal saline, atropine, pethidine, tense, Hugo point pressure, no medication, diclofenac, acetaminophen, hot shower)
Main Outcome
Duration of first, second and third stage of labor among women who received Promethazine or/and Hyoscine Measures of effect The time of labor /hour
Outcome Measure
Additional Outcome
The effectiveness of Promethazine in reducing the labor first, secong and third stage time The effectiveness of Hyoscine in reducing the labor first, secong and third stage time The effectiveness of Hyoscine & Promethazine in reducing the labor first, secong and third stage time Measures of effect No additional outcome
Study Method
Meta-analysis, Systematic review
Keyword
Butylscopolammonium Bromide; Humans; Parasympatholytics; Promethazine; Scopolamine
Contact
Marzieh Azizi [email protected]
Organisational Affiliation
Tehran University of Medical sciences
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Although there are systematic reviews such as the effectiveness of Hyoscine Butylbromide and the Duration of Labor: A Systematic Review and Meta-Analysis Study 2019, but there is no systematic review which assessed the effectiveness of both Hyoscine and Promethazine in reducing the duration of labor. <h1>Stage of review at time of this submission
Published Protocol
Review Type
Language
English
Country
Iran
Review Stage
Review Ongoing
First Submission Date
2021-08-10
Registration Date
2021-09-10
Anticipated Start Date
2021-08-01
Anticipated Completion Date
2021-12-31
Title Cn
东莨菪碱-异丙嗪对产程持续时间的效果:临床试验的系统评价与Meta分析
Title En
The effectiveness of Hyoscine-promethazine on labor duration: a systematic review and meta-analysis of clinical trials
Bilingual Status
complete