Meta AnalysisID 2788
出生后汞暴露对儿童智力的影响：系统评价与Meta分析
CRD42022333751
Whether postnatal exposure to mercury will affect the intelligence of child?
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Record Fields
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- Meta Analysis Id
- 2788
- Evidence Id
- 11346
- Core Evidence Id
- 11346
- Source Meta Analysis Id
- 2734
- Herb2 Meta Analysis Id
- HBMA002734
- Crd Id
- CRD42022333751
- Title
- Postnatal exposure to mercury affects the intelligence of children: A systematic review and meta analysis
- Review Question
- Whether postnatal exposure to mercury will affect the intelligence of child?
- Study Type Included
- We will include cohort studies and case-control studies to assess the association between body Hg concentration in children and their estimated IQ.
- Condition Being Studied
- Estimated intelligence among children with exposure to postnatal exposure to mercury.
- Participant
- Inclusion: Children. Exclusion: Adults (over 18 years of age) and elderly people (over 70).
- Animal
- Human Disease Modelled
- Intervention
- Postnatal exposure to mercury, which can be graded by total Hg levels which could be analyzed by quantified hair samples.
- Comparator Control
- Normal children with low mercury concentration in the body or without exposure of mercury.
- Main Outcome
- The effect size (β) of multiple linear regression analysis for the neuropsychological effects on log transformed hair mercury levels, inculding how transformed hair mercury levels affected the Estimated Intelligence Quotient(IQ) assessed by Wechsler Abbreviated Scale of Intelligence (WASI). Measures of effect The effect size (β) of multiple linear regression analysis.
- Outcome Measure
- Additional Outcome
- 1. Short and Working memory: Digit Span subtest WISC III (Wechsler, 2002). 2. Inhibitory control: the subtest Inhibition Errors of NEPSY II battery (Argollo et al., 2009; Korkman et al., 2007). 3. Cognitive flexibility: part B of the Brazilian version of the Trail Making Test (Seabra & Dias, 2012). Measures of effect The effect size (β) of multiple linear regression analysis.
- Study Method
- Epidemiologic, Meta-analysis, Systematic review
- Keyword
- Child; Environmental Exposure; Female; Humans; Intelligence; Maternal Exposure; Mercury
- Contact
- Jiajun Zhao [email protected]
- Organisational Affiliation
- School of Medicine, Shanghai Jiao Tong university https://www.shsmu.edu.cn/english/
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-05-24
- Registration Date
- 2022-06-04
- Anticipated Start Date
- 2022-05-01
- Anticipated Completion Date
- 2022-09-01
- Title Cn
- 出生后汞暴露对儿童智力的影响：系统评价与Meta分析
- Title En
- Postnatal exposure to mercury affects the intelligence of children: A systematic review and meta analysis
- Bilingual Status
- complete