Meta AnalysisID 2779
中低收入国家环境和职业金属（锰、汞、铁）暴露与帕金森病：叙述性综述
CRD42018099498
Is there an association between the environmental or occupational exposure to metals Mn, Hg and Fe, (Manganese, Mercury or Iron) and the risk of developing Parkinson's Disease in populations of low and middle-income coun
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2779
- Evidence Id
- 11337
- Core Evidence Id
- 11337
- Source Meta Analysis Id
- 2727
- Herb2 Meta Analysis Id
- HBMA002727
- Crd Id
- CRD42018099498
- Title
- Environmental and occupational exposure to metals (manganese, mercury, iron) and Parkinson's disease in low and middle-income countries: a narrative review
- Review Question
- Is there an association between the environmental or occupational exposure to metals Mn, Hg and Fe, (Manganese, Mercury or Iron) and the risk of developing Parkinson's Disease in populations of low and middle-income countries?
- Study Type Included
- Randomized controlled trials, non-randomized controlled trials, cluster trials, cohort studies, case-control studies, nested case-control studies, ecological studies.
- Condition Being Studied
- Neurodegenerative diseases: Parkinson's Disease. Low and middle-income countries' populations
- Participant
- Adults from low and middle-income countries. We defined “low and middle-income countries” following the World Bank criteria for 2020.
- Animal
- Human Disease Modelled
- Intervention
- Environmental or occupational exposure to metals (Manganese, Mercury, Iron).
- Comparator Control
- No exposure to environmental/occupational metals.
- Main Outcome
- The number of cases of Parkinson disease’s diagnosis, defined clinically by cardinal and additional signs. Different clinical validated definitions will be considered (The New International Parkinson Disease and Movement Disorder Society Diagnostic Criteria, The UK Parkinson’s Disease Society Brain Bank Diagnostic Criteria).
- Outcome Measure
- Additional Outcome
- Not applicable.
- Study Method
- Epidemiologic, Narrative synthesis, Prevention, Prognostic, Systematic review
- Keyword
- Environmental Exposure; Humans; Income; Ions; Iron; Manganese; Mercury; Parkinson Disease
- Contact
- Maria Ana Gonzalez Alvarez [email protected]
- Organisational Affiliation
- Pontificia Universidad Javeriana, Clinical Epidemiology Department, Bogotá. National Institute of Public Health, Environmental Health Department, Mexico City. Institute for Tropical Medicine and International Health. Charité- Universitätsmedizin, Berlin.
- Funding Source
- Non-financial support was received for conducting this review.
- Other Selection Criteria
- Final Publication
- DOI:
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Colombia, Mexico
- Review Stage
- Review Completed published
- First Submission Date
- 2018-06-04
- Registration Date
- 2018-07-03
- Anticipated Start Date
- 2018-06-04
- Anticipated Completion Date
- 2021-03-26
- Title Cn
- 中低收入国家环境和职业金属（锰、汞、铁）暴露与帕金森病：叙述性综述
- Title En
- Environmental and occupational exposure to metals (manganese, mercury, iron) and Parkinson's disease in low and middle-income countries: a narrative review
- Bilingual Status
- complete