Meta AnalysisID 2764
石杉碱甲制剂治疗阿尔茨海默病：随机临床试验的系统评价和Meta分析
CRD42012003249
What are the effectiveness and safety of Huperzine A preparations for the treatment of Alzheimer’s disease?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2764
- Evidence Id
- 11322
- Core Evidence Id
- 11322
- Source Meta Analysis Id
- 2714
- Herb2 Meta Analysis Id
- HBMA002714
- Crd Id
- CRD42012003249
- Title
- Huperzine A preparation for Alzheimer’s disease: a systematic review and meta-analysis of randomized clinical trials
- Review Question
- What are the effectiveness and safety of Huperzine A preparations for the treatment of Alzheimer’s disease?
- Study Type Included
- We will include parallel group, randomized controlled trials to assess the beneficial effects and harms of Huperzine A for treating Alzheimer’s disease regardless of blinding or publication types. Cross-over randomized trials will be included, but only outcomes at the first period of treatment will be extracted and analyzed. Quasi-randomized trials will be excluded.
- Condition Being Studied
- Alzheimer’s disease, first described by German psychiatrist Alois Alzheimer in 1906, is a progressive neurodegenerative disease characterized by cognitive deterioration together with behavioral disturbances and declining activities of daily living.
- Participant
- Inclusion: Patients with Alzheimer’s disease regardless of the disease course and severity and diagnosed with any one of the following criteria: (1)
- Animal
- Human Disease Modelled
- Intervention
- Huperzine A for patients with Alzheimer’s disease, regardless of manufactures, preparation form, dose, and duration.
- Comparator Control
- Placebo, no treatment, conventional intervention. Co-intervention is allowed if applied in all arms.
- Main Outcome
- Outcome Measure
- Additional Outcome
- Study Method
- Intervention, Meta-analysis
- Keyword
- Alkaloids; Alzheimer Disease; Humans; Neuroprotective Agents; Sesquiterpenes
- Contact
- Organisational Affiliation
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- First Submission Date
- Registration Date
- 2012-11-08
- Anticipated Start Date
- Anticipated Completion Date
- Title Cn
- 石杉碱甲制剂治疗阿尔茨海默病：随机临床试验的系统评价和Meta分析
- Title En
- Huperzine A preparation for Alzheimer’s disease: a systematic review and meta-analysis of randomized clinical trials
- Bilingual Status
- complete