Meta AnalysisID 275

番木瓜叶提取物治疗登革热患者的疗效与安全性:随机对照试验系统评价

CRD42019138959

Is Carica Papaya leaf extract effective and safe for the treatment of patients with dengue infection?

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Record Fields

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Meta Analysis Id
275
Evidence Id
8833
Core Evidence Id
8833
Source Meta Analysis Id
257
Herb2 Meta Analysis Id
HBMA000257
Crd Id
CRD42019138959
Title
What is the efficacy and safety of carica papaya leaf extract in patients with dengue infection? A systematic review of randomised controlled trials
Review Question
Is Carica Papaya leaf extract effective and safe for the treatment of patients with dengue infection?
Study Type Included
Randomised and quasi-randomised controlled trials
Condition Being Studied
Dengue viral infection
Participant
Patients with dengue virus infection (diagnosed using recognised clinical and/or laboratory parameters)
Animal
Human Disease Modelled
Intervention
Any formulations that contains Carica papaya leaf extracts (soups, powder, pills etc) in addition to standard care
Comparator Control
Placebo with standard care or standard care alone
Main Outcome
Mortality Severe complications (as per WHO criteria) Duration of hospitalisation Measures of effect We will calculate results using risk ratio for dichotomous data. The effect estimates will be presented with 95% confidence interval
Outcome Measure
Additional Outcome
Adverse effects of the intervention Laboratory parameters – such as haematocrit, platelet, liver function test Measures of effect The mean difference (MD) or standardised mean difference (SMD) and respective 95% confidence intervals will be calculated for continuous data.
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Carica; Dengue; Humans; Plant Extracts
Contact
Chin Fang Ngim [email protected]
Organisational Affiliation
Monash University Malaysia
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Malaysia
Review Stage
Review Ongoing
First Submission Date
2019-06-14
Registration Date
2019-08-15
Anticipated Start Date
2019-06-17
Anticipated Completion Date
2020-01-15
Title Cn
番木瓜叶提取物治疗登革热患者的疗效与安全性:随机对照试验系统评价
Title En
What is the efficacy and safety of carica papaya leaf extract in patients with dengue infection? A systematic review of randomised controlled trials
Bilingual Status
complete