Meta AnalysisID 2741
组胺拮抗剂类镇咳药对比安慰剂对症治疗咳嗽的疗效：随机对照试验的系统评价和Meta分析
CRD42019124528
Is the efficacy of histamine antagonist antitussive agents versus placebo on cough proven by randomized controlled trials ?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2741
- Evidence Id
- 11299
- Core Evidence Id
- 11299
- Source Meta Analysis Id
- 2691
- Herb2 Meta Analysis Id
- HBMA002691
- Crd Id
- CRD42019124528
- Title
- Efficacy of histamine antagonist antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials
- Review Question
- Is the efficacy of histamine antagonist antitussive agents versus placebo on cough proven by randomized controlled trials ?
- Study Type Included
- Randomized, controlled versus placebo trials Available in French or English.
- Condition Being Studied
- Cough, no matter the etiology.
- Participant
- Age > 2years, both genders.
- Animal
- Human Disease Modelled
- Intervention
- Administration of histamine antagonist antitussive agents for cough no matter the etiology. Search about alimemazime, oxomemazine, pimethixene, promethazine, histamine antagonist.
- Comparator Control
- Administration of placebo.
- Main Outcome
- Cough relief with a binary response pattern: yes or no.
- Outcome Measure
- Additional Outcome
- Cough relief on continous outcome : mean difference or standard mean difference : MINIMAL IMPORTANT DIFFERENCE Duration of cough Quality of life Adverse events : for example dizziness, nausea, vomiting, drowsiness, constipation, diarrhea, hallucination, addiction… Serious Adverse Events (SAE) Repercussions on sleep.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Antitussive Agents; Cough; Histamine Antagonists; Humans; Randomized Controlled Trials as Topic
- Contact
- Marc Adou [email protected]
- Organisational Affiliation
- Département de Médecine Générale de la Faculté Lyon Est https://lyon-est.univ-lyon1.fr/
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English, French
- Country
- France
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-02-11
- Registration Date
- 2019-03-14
- Anticipated Start Date
- 2019-02-01
- Anticipated Completion Date
- 2019-03-12
- Title Cn
- 组胺拮抗剂类镇咳药对比安慰剂对症治疗咳嗽的疗效：随机对照试验的系统评价和Meta分析
- Title En
- Efficacy of histamine antagonist antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials
- Bilingual Status
- complete