Meta AnalysisID 2738
鼻内糖皮质激素、白三烯受体拮抗剂、减充血剂和第二代组胺H1拮抗剂治疗成人过敏性鼻炎的疗效比较：系统评价和网状Meta分析
CRD42014007115
To assess the effects of intranasal steroids, leukotriene antagonists, decongestant, and second generation Histamine H1 Antagonists in adult patients with allergic rhinitis.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2738
- Evidence Id
- 11296
- Core Evidence Id
- 11296
- Source Meta Analysis Id
- 2688
- Herb2 Meta Analysis Id
- HBMA002688
- Crd Id
- CRD42014007115
- Title
- Comparative effectiveness of intranasal steroids, leukotriene antagonists, decongestant, and second generation Histamine H1 Antagonists in allergic rhinitis of adults: systematic review and network meta-analysis
- Review Question
- To assess the effects of intranasal steroids, leukotriene antagonists, decongestant, and second generation Histamine H1 Antagonists in adult patients with allergic rhinitis.
- Study Type Included
- Randomised, double-blinded, parallel group design clinical trials will be included, otherwise excluded.
- Condition Being Studied
- Allergic rhinitis is a common disease characterised by nasal itch, sneezing, rhinorrhoea and nasal obstruction, sometimes accompanied by allergic conjunctivitis. It is divided into seasonal allergic rhinitis and persistent allergic rhinitis.
- Participant
- Patients older than 18 years with seasonal or persistent allergic rhinitis without asthma.
- Animal
- Human Disease Modelled
- Intervention
- Any single or combination treatment of intranasal steroids, leukotriene antagonists, decongestants, or second generation Histamine H1 Antagonists compared with placebo will be included. Other treatments will be excluded.
- Comparator Control
- Placebo.
- Main Outcome
- Total nasal symptoms.
- Outcome Measure
- Additional Outcome
- Nasal blockage, nasal discharge, sneezing, nasal itch, total nasal symptoms, nasal resistance, eye symptoms and quality of life score.
- Study Method
- Intervention, Meta-analysis, Network_Meta-analysis
- Keyword
- Administration, Intranasal; Adult; Histamine H1 Antagonists; Humans; Leukotriene Antagonists; Nasal Decongestants; Rhinitis, Allergic, Perennial; Steroids
- Contact
- wu haiyan [email protected]
- Organisational Affiliation
- department of otorhinolaryngology, the affiliated jiangyin hospital of southeast university medical college
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2014-01-13
- Anticipated Start Date
- 2013-12-20
- Anticipated Completion Date
- 2015-01-01
- Title Cn
- 鼻内糖皮质激素、白三烯受体拮抗剂、减充血剂和第二代组胺H1拮抗剂治疗成人过敏性鼻炎的疗效比较：系统评价和网状Meta分析
- Title En
- Comparative effectiveness of intranasal steroids, leukotriene antagonists, decongestant, and second generation Histamine H1 Antagonists in allergic rhinitis of adults: systematic review and network meta-analysis
- Bilingual Status
- complete