Meta AnalysisID 267
冬虫夏草对维持性腹膜透析患者的效果与安全性：系统评价与Meta分析
CRD42021238581
The purpose of this randomized controlled trial meta-analysis was to evaluate the efficacy and safety of cordyceps sinensis in patients undergoing maintenance peritoneal dialysis.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 267
- Evidence Id
- 8825
- Core Evidence Id
- 8825
- Source Meta Analysis Id
- 248
- Herb2 Meta Analysis Id
- HBMA000248
- Crd Id
- CRD42021238581
- Title
- Effect and safety of cordyceps sinensis on maintenance peritoneal dialysis patients: a systematic review and meta-analysis
- Review Question
- The purpose of this randomized controlled trial meta-analysis was to evaluate the efficacy and safety of cordyceps sinensis in patients undergoing maintenance peritoneal dialysis.
- Study Type Included
- Randomized controlled trials (RCTs) will be included.
- Condition Being Studied
- Peritoneal dialysis is a commonly used method in the treatment of CRF, but long-term peritoneal dialysis will increase the risk of malnutrition in patients, leading to micro-inflammatory state in the body, and gradual loss of residual renal function, affecting the prognosis. Therefore, it is of great significance to select appropriate drug-assisted dialysis therapy to protect the nutritional status and residual renal function of CRF patients. Studies have found that Cordyceps sinensis can delay the progression of the disease and improve renal function.
- Participant
- Inclusion criteria: duration of Peritoneal dialysis: > 6 months; Over 18 years of age; Stable condition in recent 3 months; (4) get informed consent, sign informed with the letter. Exclusion criteria: (1) drug-induced nephropathy and acute renal failure; Lung and heart diseases caused by other causes; (3) Patients with tumor or severe liver disease; (4) at the same time receive other renal replacement therapy; People with mental illness; Allergic constitution.
- Animal
- Human Disease Modelled
- Intervention
- Both groups received continuous ambulatory peritoneal dialysis, 4 to 6 hours each time, 4 times a day. The observation group combined with cordyceps sinensis preparation on the basis of the control group. The course of treatment in both groups was 12 w.
- Comparator Control
- The control group received routine treatment, including symptomatic treatment such as protecting renal function, correcting calcium and phosphorus metabolism, correcting anemia, lowering blood pressure, etc., and paying attention to rest, high-quality diet, low-salt, low-glycolipid diet.
- Main Outcome
- C-reactive protein，hemoglobin，albumin，Serum creatinine Measures of effect Relative risks, odds ratios
- Outcome Measure
- Additional Outcome
- Tumor necrosis factor alpha，Interleukin 6，total protein，prealbumin，urea nitrogen，Beta 2 microglobulin，total cholesterol，triglyceride，low density lipoprotein Measures of effect Relative risks, odds ratios
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Cordyceps; Humans; Peritoneal Dialysis
- Contact
- Xiaojing Hu [email protected]
- Organisational Affiliation
- The First Affiliated Hospital of Henan University of Traditional Chinese Medicine https://www.hnzhy.com/
- Funding Source
- National Natural Science Foundation of China Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> No.8197151655
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-02-21
- Registration Date
- 2021-05-24
- Anticipated Start Date
- 2021-02-28
- Anticipated Completion Date
- 2021-08-31
- Title Cn
- 冬虫夏草对维持性腹膜透析患者的效果与安全性：系统评价与Meta分析
- Title En
- Effect and safety of cordyceps sinensis on maintenance peritoneal dialysis patients: a systematic review and meta-analysis
- Bilingual Status
- complete