Meta AnalysisID 2612
低容量聚乙二醇联合抗坏血酸加辅助药物方案不劣于低容量肠道清洁方案：随机对照试验的Meta分析
CRD42020167426
High volume and low volume PEG-based regimens are recommended for bowel preparation, both volume of which are too much large.We want to know whether lower-volume polyethylene glycol with ascorbic acid plus adjunctive dru
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2612
- Evidence Id
- 11170
- Core Evidence Id
- 11170
- Source Meta Analysis Id
- 2562
- Herb2 Meta Analysis Id
- HBMA002562
- Crd Id
- CRD42020167426
- Title
- Lower-volume Polyethylene Glycol with Ascorbic Acid plus Adjunctive Drugs Preparations are Not Inferior to Low-volume Bowel Cleansing Regimens: a Meta-analysis of Randomized, Controlled Trials
- Review Question
- High volume and low volume PEG-based regimens are recommended for bowel preparation, both volume of which are too much large.We want to know whether lower-volume polyethylene glycol with ascorbic acid plus adjunctive drugs preparations are inferior to low-volume bowel cleansing regimens for bowel preparation?
- Study Type Included
- For the purpose of our meta-analysis, we will consider all randomized control trials meeting the following inclusion criteria: (I) Population: all adults undergoing elective colonoscopy, irrespective of the indication. (II) Intervention: all 1L polyethylene glycol with ascorbic acid plus adjuvants bowel preparation regimens. (III) Comparison: all 2L polyethylene glycol with ascorbic acid regimens. (IV) Outcome: bowel preparation effect was recorded as the primary outcome. Secondary outcomes included compliance with the recommend regimen, willingness to repeat the same bowel solution, side effects. Studies will be excluded if meeting at least one of the following exclusion criteria: (I) Essential information not available; (II) Study investigating bowel preparation regimen in special patients, such as pediatric patients, patients with a history of colorectal resection, inflammatory bowel disease patients or patients with a previous poor bowel preparation. (III) Study investigating bowel preparation regimens not available.
- Condition Being Studied
- Colonoscopy.Bowel preparation
- Participant
- Patients who undergo a colonoscopy for any indications.
- Animal
- Human Disease Modelled
- Intervention
- 1L polyethylene glycol with ascorbic acid plus adjunctive drugs preparations
- Comparator Control
- 2L polyethylene glycol with ascorbic acid regimens
- Main Outcome
- bowel preparation effect Measures of effect Boston bowel preparation score (BBPS), Adenoma detection rate (ADR)
- Outcome Measure
- Additional Outcome
- Acceptability, side effects Measures of effect Willingness to repeat, abdominal pain, bloating, nausea, vomiting, sleep disturbance
- Study Method
- Meta-analysis, Prognostic, Systematic review
- Keyword
- Ascorbic Acid; Cathartics; Colonoscopy; Humans; Polyethylene Glycols; Randomized Controlled Trials as Topic
- Contact
- Rush Yuan [email protected]
- Organisational Affiliation
- Ningbo University https://www.nbu.edu.cn/
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-01-31
- Registration Date
- 2020-04-28
- Anticipated Start Date
- 2020-02-02
- Anticipated Completion Date
- 2020-03-02
- Title Cn
- 低容量聚乙二醇联合抗坏血酸加辅助药物方案不劣于低容量肠道清洁方案：随机对照试验的Meta分析
- Title En
- Lower-volume Polyethylene Glycol with Ascorbic Acid plus Adjunctive Drugs Preparations are Not Inferior to Low-volume Bowel Cleansing Regimens: a Meta-analysis of Randomized, Controlled Trials
- Bilingual Status
- complete