Meta AnalysisID 2607
哪种口服肠道准备方案可为择期门诊结肠镜检查提供更好的清洁效果：匹可硫酸钠（PICO）还是聚乙二醇（PEG）？系统评价与Meta分析
CRD42016050059
Which oral bowel preparation regimen provides a better cleansing for elective outpatient colonoscopy: sodium picosulphate (PICO) or polyethylene glycol (PEG)?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2607
- Evidence Id
- 11165
- Core Evidence Id
- 11165
- Source Meta Analysis Id
- 2557
- Herb2 Meta Analysis Id
- HBMA002557
- Crd Id
- CRD42016050059
- Title
- Which oral bowel preparation regimen provides a better cleansing for elective outpatient colonoscopy: sodium picosulphate (PICO) or polyethylene glycol (PEG)? Systematic review and meta-analysis
- Review Question
- Which oral bowel preparation regimen provides a better cleansing for elective outpatient colonoscopy: sodium picosulphate (PICO) or polyethylene glycol (PEG)?
- Study Type Included
- Randomized clinical trials studying oral bowel cleansing, comparing sodium picosulphate and polyethylene glycol regimens for cleansing effectiveness and tolerability. Retrospective studies will be excluded.
- Condition Being Studied
- Cathartics / bowel preparation solutions for colonoscopy.
- Participant
- Outpatient adults (18 years or older) scheduled for elective colonoscopy who have undergone bowel cleansing at home or at clinic.
- Animal
- Human Disease Modelled
- Intervention
- PICO. Regimens based in the sodium picosulphate arm, with or without adjuncts or dietary restrictions, for bowel cleansing before colonoscopy. Studies involving combinations of two or more different products in the same regimen (sodium picosulphate, polyethylene glycol, mannitol or sodium sulphate) or associations with enemas or enteroclysis, will be excluded.
- Comparator Control
- PEG. Regimens based in polyethylene glycol arm, with or without adjuncts or dietary restrictions, for bowel cleansing before colonoscopy. Studies involving combinations of two or more different products in the same regimen (sodium picosulphate, polyethylene glycol, mannitol or sodium sulphate) or associations with enemas or enteroclysis, will be excluded.
- Main Outcome
- Bowel cleansing success, defined as the number of patients with successful cleansing of the bowel by the study or by the assessment score used and categorized as excellent, adequate, good or clean. Measures of effect Measurement at the time of colonoscopy.
- Outcome Measure
- Additional Outcome
- Tolerability (or adherence to the bowel cleansing protocol), defined as the number of patients who have ingested the entire bowel cleansing preparation or the minimum established by the study as acceptable. Adverse events prevalence, defined as the number of patients who experienced any symptoms, discomfort, signs or adverse events due to colon cleansing. Polyp detection rate, defined as the number of patients with at least one polyp detected during colonoscopy. Adenoma detection rate, defined as the number of patients with at least one adenoma detected during colonoscopy. Measures of effect Measurement at the time of colonoscopy and after histopathological evalution is completed.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Citrates; Colonoscopy; Elective Surgical Procedures; Humans; Organometallic Compounds; Outpatients; Picolines; Polyethylene Glycols; Preoperative Care; Preoperative Period; Treatment Outcome
- Contact
- Rodrigo Rocha [email protected]
- Organisational Affiliation
- Gastrointestinal Endoscopy Unit, Department of Gastroenterology, University of Sao Paulo School of Medicine http://www.fm.usp.br
- Funding Source
- Gastrointestinal Endoscopy Unit, Department of Gastroenterology, University of Sao Paulo School of Medicine
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Brazil
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2016-10-23
- Anticipated Start Date
- 2016-02-01
- Anticipated Completion Date
- 2016-12-31
- Title Cn
- 哪种口服肠道准备方案可为择期门诊结肠镜检查提供更好的清洁效果：匹可硫酸钠（PICO）还是聚乙二醇（PEG）？系统评价与Meta分析
- Title En
- Which oral bowel preparation regimen provides a better cleansing for elective outpatient colonoscopy: sodium picosulphate (PICO) or polyethylene glycol (PEG)? Systematic review and meta-analysis
- Bilingual Status
- complete