Meta AnalysisID 2549
硫酸氨基葡萄糖：健康结局的伞状评价
CRD42020179570
The aim of this umbrella review is to summarize all health outcomes that are associated with the use of glucosamine sulphate (GS) in human beings.
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2549
- Evidence Id
- 11107
- Core Evidence Id
- 11107
- Source Meta Analysis Id
- 2497
- Herb2 Meta Analysis Id
- HBMA002497
- Crd Id
- CRD42020179570
- Title
- Glucosamine sulphate: an umbrella review of health outcomes
- Review Question
- The aim of this umbrella review is to summarize all health outcomes that are associated with the use of glucosamine sulphate (GS) in human beings.
- Study Type Included
- We will include systematic reviews with or without formal meta-analysis that evaluated observational studies with longitudinal (prospective or retrospective) design reporting on health outcomes in subjects taking GS versus those not taking this medication and not taking any other similar medication (e.g. chondrointin sulphate). We will include systematic reviews with or with formal meta-analysis of randomized controlled trials (RCTs) in which at least one group used GS and one placebo.
- Condition Being Studied
- GS is traditionally used for knee osteoarthritis. However this will be an umbrella review summarizing all the possible health outcomes. Therefore, any condition requiring GS will be considered.
- Participant
- No restrictions regarding participants and populations will be posed.
- Animal
- Human Disease Modelled
- Intervention
- Glucosamine sulphate, at any dosage.
- Comparator Control
- Placebo for RCTs and not taking GS for observational studies.
- Main Outcome
- All health outcomes (e.g. pain, function, disability rate) will be considered as primary/co-primary outcomes Measures of effect According to the original article, we will extract single study-specific risk estimates (i.e., mean difference, standardized mean difference, risk ratio, odds ratio, hazard ratio, or incident risk ratio, or other reported effect sizes) with 95% confidence intervals (CIs),
- Outcome Measure
- Additional Outcome
- None. Measures of effect Not applicable.
- Study Method
- Epidemiologic, Intervention, Review of reviews, Systematic review
- Keyword
- Glucosamine; Humans; Osteoarthritis, Knee
- Contact
- Lee Smith [email protected]
- Organisational Affiliation
- Anglia Ruskin University
- Funding Source
- Other Selection Criteria
- Final Publication
- Veronese N, Demurtas J, Smith L, Reginster JY, Bruyère O, Beaudart C, Honvo G, Maggi S; on behalf on the European Geriatric Medicine Society Special Interest Groups in Systematic Reviews and Meta-Analyses and Arthritis. Glucosamine sulphate: an umbrella review of health outcomes. Ther Adv Musculoskelet Dis. 2020 Dec 26;12:1759720X20975927. doi: 10.1177/1759720X20975927. PMID: 33488785; PMCID: PMC7768322.
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Completed published
- First Submission Date
- 2020-04-11
- Registration Date
- 2020-09-30
- Anticipated Start Date
- 2020-04-13
- Anticipated Completion Date
- 2020-12-31
- Title Cn
- 硫酸氨基葡萄糖：健康结局的伞状评价
- Title En
- Glucosamine sulphate: an umbrella review of health outcomes
- Bilingual Status
- complete