Meta AnalysisID 2543
抗脱酰胺麦胶蛋白肽IgG抗体诊断IgA缺乏或2岁以下儿童乳糜泻的准确性：一项系统评价和Meta分析
CRD42020214578
What is the diagnostic accuracy of the anti-deamidated gliadin peptide IgG antibodies for diagnosing celiac disease in patients with IgA deficiency or less than two years old?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2543
- Evidence Id
- 11101
- Core Evidence Id
- 11101
- Source Meta Analysis Id
- 2491
- Herb2 Meta Analysis Id
- HBMA002491
- Crd Id
- CRD42020214578
- Title
- Diagnostic accuracy of anti-deamidated gliadin peptide IgG antibodies for diagnosing celiac disease in patients with IgA deficiency or children under 2 years: a Systematic Review and Meta-Analysis
- Review Question
- What is the diagnostic accuracy of the anti-deamidated gliadin peptide IgG antibodies for diagnosing celiac disease in patients with IgA deficiency or less than two years old?
- Study Type Included
- Diagnostic accuracy studies, in principle, cross-sectional studies and case-control studies. All studies must have anti-deamidated gliadin peptide IgG antibodies (index test) validated with an endoscopic duodenal biopsy (gold standard test) or previous definitive CD diagnostic.
- Condition Being Studied
- Celiac Disease (CD)
- Participant
- Individuals (any age) with IgA deficiency or children under 2 years.
- Animal
- Human Disease Modelled
- Intervention
- anti-deamidated gliadin peptide IgG antibodies
- Comparator Control
- Endoscopic duodenal biopsy or previous definitive CD diagnostic.
- Main Outcome
- The main objective of our study is to evaluate the diagnostic capability of anti-gliadin deamidated IgG antibodies in differentiating the presence or absence of celiac disease in patients with IgA deficiency or children under 2y. Measures of effect Diagnostic accuracy must be measured by accuracy, true positive (TP) rate, false positive (FN) rate, true negative (TN) rate, false negative (FN) rate, negative predictive value, positive predictive value, sensibility, specificity, overall accuracy, positive and negative likelihood ratio, whenever data allows.
- Outcome Measure
- Additional Outcome
- Not applicable. Measures of effect Not applicable.
- Study Method
- Diagnostic, Meta-analysis, Systematic review
- Keyword
- Celiac Disease; Child; Gliadin; Humans; IgA Deficiency; Immunoglobulin G; Infant; Peptides
- Contact
- Ney Boa-Sorte [email protected]
- Organisational Affiliation
- Hosanah Oliveira Pediatric Center, Federal University of Bahia R Padre Feijo 29, Canela, Salvador-BA, Brazil Zip Code 40110-170
- Funding Source
- Not applicable Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> Not applicable
- Other Selection Criteria
- Final Publication
- Not applicable in this moment
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English, Portuguese-Brazil
- Country
- Brazil
- Review Stage
- Review Completed published
- First Submission Date
- 2020-10-15
- Registration Date
- 2020-11-15
- Anticipated Start Date
- 2020-08-03
- Anticipated Completion Date
- 2021-01-31
- Title Cn
- 抗脱酰胺麦胶蛋白肽IgG抗体诊断IgA缺乏或2岁以下儿童乳糜泻的准确性：一项系统评价和Meta分析
- Title En
- Diagnostic accuracy of anti-deamidated gliadin peptide IgG antibodies for diagnosing celiac disease in patients with IgA deficiency or children under 2 years: a Systematic Review and Meta-Analysis
- Bilingual Status
- complete