Meta AnalysisID 2538

人参皂苷Rh1的生物活性:一项系统评价

CRD42016051391

This study is being conducted to review the pharmacological effects of ginsenoside Rh1.

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Record Fields

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Meta Analysis Id
2538
Evidence Id
11096
Core Evidence Id
11096
Source Meta Analysis Id
2486
Herb2 Meta Analysis Id
HBMA002486
Crd Id
CRD42016051391
Title
Bioactive activities of ginseng ginsenoside Rh1: a systematic review
Review Question
This study is being conducted to review the pharmacological effects of ginsenoside Rh1.
Study Type Included
Original articles except book chapters, posters, theses, editorials, conference papers, case reports and review papers.
Condition Being Studied
Ginseng, a traditional herb medicine, has gained increasing popularity in the world market due to various medicinal properties, such as anticancer, anti-inflammatory, enhancing immune response and cognition, hepatoprotective effects and protection against neurological disorders (1,2). These effects are closely related to the presence of various bioactive compounds in which ginsenosides are the major components (3-6). There are more than 30 ginsenosides which can be classified into at least 4 types of ginsenosides in Ginseng (7). Among these, Ginsenoside Rh1, a protopanaxatriol derivative, has been found to have stimulating effects on the central nervous system such as anti-fatigue and antihypertensive effects, anabolic stimulation, enhance mental acuity and intellectual performance (8). In addition, many studies have shown that ginsenoside Rh1 has neuroprotective effects, potential antineoplastic effects and acts as an adjuvant therapy in chronic inflammatory diseases to dexamethasone (9-11). We aim to systematically review the pharmacological effects of bioactive ginsenoside Rh1 on both human and animal subjects from the literature. References: 1.
Participant
Animal
Human Disease Modelled
Intervention
Ginsenoside Rh1, either administered alone or in combined with other regimes.
Comparator Control
Where there are control groups such as placebo or other medications, a comparison will be performed.
Main Outcome
Outcome Measure
Additional Outcome
Study Method
Systematic review
Keyword
Complementary Therapies; Drugs, Chinese Herbal; Ginsenosides; Humans; Panax; Plant Extracts; Treatment Outcome
Contact
Organisational Affiliation
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Egypt, Japan, Vietnam
Review Stage
First Submission Date
Registration Date
2016-11-12
Anticipated Start Date
Anticipated Completion Date
Title Cn
人参皂苷Rh1的生物活性:一项系统评价
Title En
Bioactive activities of ginseng ginsenoside Rh1: a systematic review
Bilingual Status
complete