Meta AnalysisID 2520
多奈哌齐、加兰他敏、卡巴拉汀和美金刚治疗阿尔茨海默病：一项贝叶斯网状Meta分析
CRD42018109231
To investigate the techniques available for the assessment, and to compare the effectiveness and tolerability of donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2520
- Evidence Id
- 11078
- Core Evidence Id
- 11078
- Source Meta Analysis Id
- 2470
- Herb2 Meta Analysis Id
- HBMA002470
- Crd Id
- CRD42018109231
- Title
- Donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease: a Bayesian network meta-analysis
- Review Question
- To investigate the techniques available for the assessment, and to compare the effectiveness and tolerability of donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease.
- Study Type Included
- Only RCTs will be included.
- Condition Being Studied
- Alzheimer's disease.
- Participant
- Adults with Alzheimer's disease (as dignosed using any recognised diagnostic criteria).
- Animal
- Human Disease Modelled
- Intervention
- Monotherapy or combined therapy using donepezil, galantamine, rivastigmine and memantine.
- Comparator Control
- Monotherapy or combined therapy using donepezil, galantamine, rivastigmine and memantine; placebo or blank control.
- Main Outcome
- ADCS-CGIC, CIBIC+, CDR;ADAS-ADL, DAD; ADAS-COG, MMSE, SIB; NPI.
- Outcome Measure
- Additional Outcome
- Compliance; adverse events.
- Study Method
- Intervention, Meta-analysis, Network meta-analysis, Systematic review
- Keyword
- Adult; Aged; Alzheimer Disease; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Drug Therapy; Drug Therapy, Combination; Galantamine; Humans; Indans; Memantine; Piperidines; Rivastigmine; Treatment Outcome
- Contact
- Yuting Duan [email protected]
- Organisational Affiliation
- Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medcine
- Funding Source
- National Natural Science Foundation (Project No.81873375); First-class Discipline Construction Foundation of Guangzhou University of Chinese Medicine (Chinese medicine discipline) ;Young Top Talent Project of Scientific and Technological Innovation in Special Support Plan for Training High-level Talents in Guangdong (no. 2017TQ04R627) and Guangdong Natural Science Foundation (Project No.2016A030310290).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2018-09-07
- Registration Date
- 2018-09-19
- Anticipated Start Date
- 2018-07-06
- Anticipated Completion Date
- 2018-12-31
- Title Cn
- 多奈哌齐、加兰他敏、卡巴拉汀和美金刚治疗阿尔茨海默病：一项贝叶斯网状Meta分析
- Title En
- Donepezil, galantamine, rivastigmine and memantine for Alzheimer's disease: a Bayesian network meta-analysis
- Bilingual Status
- complete