Meta AnalysisID 2518
乳糖不耐受的系统评价和Meta分析：全球、区域和国家层面10岁及以上儿童与成人的患病率
CRD42022373626
The objective is to present an updated systematic review and meta-analysis on the global, regional, and national prevalence of lactose intolerance, estimate the global burden, and assess variation in estimates between di
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Record Fields
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- Meta Analysis Id
- 2518
- Evidence Id
- 11076
- Core Evidence Id
- 11076
- Source Meta Analysis Id
- 2468
- Herb2 Meta Analysis Id
- HBMA002468
- Crd Id
- CRD42022373626
- Title
- Systematic review and meta-analysis of lactose intolerance; the global, regional, and national prevalence in adults and children aged 10 years or older.
- Review Question
- The objective is to present an updated systematic review and meta-analysis on the global, regional, and national prevalence of lactose intolerance, estimate the global burden, and assess variation in estimates between different methods.
- Study Type Included
- We will evaluate studies presenting prevalence data of lactose intolerance (LI) or lactase persistence (LP) including cross sectional and prospective studies using genotyping, hydrogen breath test (HBT), lactose tolerance test (LTT) or other methods. Studies with no prevalence data, no data on the number of participants, insufficiently described methodology, or potential bias of the population, which doesn't represent a general population, will be excluded.
- Condition Being Studied
- Lactose intolerance in adults and children aged 10 years or older.
- Participant
- Inclusion: Studies presenting data on the prevalence of lactose intolerance or lactase persistence among adults and children aged 10 years or older. Exclusion: Studies using self-reported data and inpatients and outpatients at gastrointestinal wards and studies in children younger than 10 years old. Additionally, Studies with no prevalence data, no data on the number of participants, insufficiently described methodology, or potential bias of the population, which doesn't represent a general population, will be excluded.
- Animal
- Human Disease Modelled
- Intervention
- No intervention will be studied directly. A variety of methods will be used for determining lactose intolerance (LI) or lactase persistence (LP), including genotyping, hydrogen breath test (HBT), lactose tolerance test (LTT), and urinary galactose excretion.
- Comparator Control
- We will compare studies using genotyping, hydrogen breath test (HBT), lactose tolerance test (LTT), or other methods.
- Main Outcome
- Prevalence of lactose intolerance.
- Outcome Measure
- Additional Outcome
- Estimate prevalence of lactose intolerance globally, regionally, and nationally. Estimate the global burden, and assess variation in estimates between different methods.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adult; Child; Cost of Illness; Global Health; Humans; Lactose Intolerance; Prevalence
- Contact
- Alireza Vahdatinia [email protected]
- Organisational Affiliation
- Mazandaran University of Medical Sciences
- Funding Source
- Funded by MAZUMS (Mazandaran University of Medical Sciences)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-11-08
- Registration Date
- 2022-11-19
- Anticipated Start Date
- 2022-11-05
- Anticipated Completion Date
- 2023-05-25
- Title Cn
- 乳糖不耐受的系统评价和Meta分析：全球、区域和国家层面10岁及以上儿童与成人的患病率
- Title En
- Systematic review and meta-analysis of lactose intolerance; the global, regional, and national prevalence in adults and children aged 10 years or older.
- Bilingual Status
- complete