Meta AnalysisID 2502
黄酮醇对心血管代谢生物标志物影响的个体间反应差异：系统评价方案和Meta分析
CRD42016037074
To assess the inter-individual variability in response to the impact of flavonols on biomarkers of cardiometabolic diseases.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2502
- Evidence Id
- 11060
- Core Evidence Id
- 11060
- Source Meta Analysis Id
- 2452
- Herb2 Meta Analysis Id
- HBMA002452
- Crd Id
- CRD42016037074
- Title
- Inter-individual variability in response to the impact of flavonols on cardiometabolic biomarkers: a systematic review protocol and meta-analysis
- Review Question
- To assess the inter-individual variability in response to the impact of flavonols on biomarkers of cardiometabolic diseases.
- Study Type Included
- Randomized clinical trials (RCTs) assessing the effects of flavonols on cardiometabolic biomarkers. Exclusion: case series, case reports, cohort studies, case-control studies, and cross-sectional studies
- Condition Being Studied
- Cardiovascular risk factors in human subjects.
- Participant
- Human subjects, including both sexes and without any age restriction. Exclusion: studies conducted in animals and in vitro.
- Animal
- Human Disease Modelled
- Intervention
- Studies evaluating dietary interventions with flavonols. No treatment period restrictions will be imposed
- Comparator Control
- The studies must have been included a control group, whether receiving a placebo (a group of participants who were not exposed to the flavonol-food sources) or simply not being exposed to anything.
- Main Outcome
- Outcomes related to flow-mediated dilatation (FMD), blood pressure, plasma or serum lipid levels (triglycerides, total-, HDL- and LDL-cholesterol), exercise capacity, platelet aggregation, body mass index, waist circumference, glucose, fasting insulin, glycated haemoglobin (HbA1c), and insulin resistance (HOMA-IR).
- Outcome Measure
- Additional Outcome
- Study Method
- Keyword
- Biomarkers; Flavonols; Humans
- Contact
- Dr Pinto [email protected]
- Organisational Affiliation
- European Union COST (Cooperation in Science and Technology) Action FA1403 “Interindividual variation in response to consumption of plant food bioactives and determinants involved (POSITIVe)” (http://www.cost.eu/COST_Actions/fa/Actions/FA1403; http://www6.inra.fr/cost-positive).
- Funding Source
- European Union COST (Cooperation in Science and Technology) Action FA1403 “Interindividual variation in response to consumption of plant food bioactives and determinants involved (POSITIVe)”
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England, Northern Ireland, Scotland, Cyprus, Germany, Greece, Macedonia, Former Yugoslav Republic Of, Netherlands, Portugal, Spain
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2016-03-29
- Anticipated Start Date
- 2015-12-08
- Anticipated Completion Date
- 2016-09-30
- Title Cn
- 黄酮醇对心血管代谢生物标志物影响的个体间反应差异：系统评价方案和Meta分析
- Title En
- Inter-individual variability in response to the impact of flavonols on cardiometabolic biomarkers: a systematic review protocol and meta-analysis
- Bilingual Status
- complete