Meta AnalysisID 2498
黄烷醇对糖尿病患者血压和血管功能的影响：Meta分析
CRD42018112229
What is the effect of flavanols, extracted from the cocoa bean, on blood pressure (systolic and diastolic) and vascular function in patients with diabetes mellitus?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2498
- Evidence Id
- 11056
- Core Evidence Id
- 11056
- Source Meta Analysis Id
- 2448
- Herb2 Meta Analysis Id
- HBMA002448
- Crd Id
- CRD42018112229
- Title
- The effects of flavanols on blood pressure and vascular function in patients with diabetes mellitus: a meta-analysis
- Review Question
- What is the effect of flavanols, extracted from the cocoa bean, on blood pressure (systolic and diastolic) and vascular function in patients with diabetes mellitus?
- Study Type Included
- Randomized Controlled Trials
- Condition Being Studied
- Cardiovascular complications in diabetes mellitus.
- Participant
- Inclusion: diabetes mellitus, human (men and women), all ages Exclusion: animals, cells In case of mixed populations (only part of the participants are diabetes patients) articles will be included but will be placed in a subgroup.
- Animal
- Human Disease Modelled
- Intervention
- Randomized Controlled Trials in which patients are given a certain amount of flavanols, extracted from the cocoa bean, in any form (chocolate bars, capsules, powder, etc.). These interventions may be acute or chronically.
- Comparator Control
- Randomized Controlled Trials in which the control population do not get a certain amount of flavanols in any form. The control population do or do not get a placebo (any type of placebo is allowed, the only condition is that it has to be free of flavanols).
- Main Outcome
- Change in blood pressure (systolic and diastolic) after the intake of a flavanol-rich substances (capsules, chocolate bars, powder, etc.). There are no conditions set up about how these measurements have to be executed (holter monitoring, single measurement, etc.). Measures of effect The blood pressure measurements had to be performed before and immediately after the intake or during the hours following the intake. The measurements have to start at latest 6 hours post intake.
- Outcome Measure
- Additional Outcome
- Vascular measurements like flow-mediated dilatation, arterial stiffness, pulse wave velocity etc., which can be used to partly explain the blood pressure changes. Measures of effect The measurements had to be performed before and immediately after the intake or during the hours following the intake. The measurements have to start at latest 6 hours post intake.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Blood Pressure; Blood Pressure Determination; Humans; Polyphenols
- Contact
- Anouk Tanghe [email protected]
- Organisational Affiliation
- University of Ghent, Faculty of Medicine and Health Sciences, Department of Physical and Motor Rehabilitation https://www.ugent.be/ge/revaki/en
- Funding Source
- University of Ghent
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Belgium
- Review Stage
- Review Ongoing
- First Submission Date
- 2018-10-12
- Registration Date
- 2018-10-25
- Anticipated Start Date
- 2018-04-01
- Anticipated Completion Date
- 2019-09-30
- Title Cn
- 黄烷醇对糖尿病患者血压和血管功能的影响：Meta分析
- Title En
- The effects of flavanols on blood pressure and vascular function in patients with diabetes mellitus: a meta-analysis
- Bilingual Status
- complete