Meta AnalysisID 2494
比较来曲唑与枸橼酸氯米芬对PCOS女性排卵作用的系统评价和Meta分析
CRD42023390290
What is the effect of letrozole compared to clomiphene citrate on the ovulation rate in women with polycystic ovary syndrome?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2494
- Evidence Id
- 11052
- Core Evidence Id
- 11052
- Source Meta Analysis Id
- 2445
- Herb2 Meta Analysis Id
- HBMA002445
- Crd Id
- CRD42023390290
- Title
- A systematic review and meta‐analysis comparing the effect of letrozole and clomiphene citrate in ovulation PCOS women.
- Review Question
- What is the effect of letrozole compared to clomiphene citrate on the ovulation rate in women with polycystic ovary syndrome?
- Study Type Included
- Randomized controlled trial (RCT) with either parallel or cross-over design.
- Condition Being Studied
- Women with polycystic ovary syndrome
- Participant
- Women with polycystic ovary syndrome
- Animal
- Human Disease Modelled
- Intervention
- Letrozole without any adjuncts in any dose. Ovulation induction therapy with letrozole followed by timed intercourse or intrauterine insemination.
- Comparator Control
- Clomiphene citrate without any adjuncts in any dose. Ovulation induction therapy with letrozole followed by timed intercourse or intrauterine insemination.
- Main Outcome
- Ovulation rate， clinical pregnancy rate， and live birth rate.
- Outcome Measure
- Additional Outcome
- Cardiometabolic and hormonal parameters such as fasting blood glucose, fasting insulin, insulin resistance (HOMA-IR), FSH, LH, and DHEA-S levels.
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Citrates; Clomiphene; Female; Humans; Letrozole; Ovulation; Polycystic Ovary Syndrome
- Contact
- javad Heshmati [email protected]
- Organisational Affiliation
- Department of Nutrition, School of Public Health, Iran university of medical sciences, Tehran, Iran
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-01-08
- Registration Date
- 2023-01-19
- Anticipated Start Date
- 2023-01-09
- Anticipated Completion Date
- 2023-02-28
- Title Cn
- 比较来曲唑与枸橼酸氯米芬对PCOS女性排卵作用的系统评价和Meta分析
- Title En
- A systematic review and meta‐analysis comparing the effect of letrozole and clomiphene citrate in ovulation PCOS women.
- Bilingual Status
- complete