Meta AnalysisID 2467

N-乙酰半胱氨酸和维生素E对输血依赖性地中海贫血患者氧化状态和血液参数的影响:一项系统评价与网状Meta分析

CRD42021250425

What is the effect of N-acetyl cysteine and vitamin E on oxidative status and blood parameters in transfusion dependent thalassemia patients?

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Record Fields

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Meta Analysis Id
2467
Evidence Id
11025
Core Evidence Id
11025
Source Meta Analysis Id
2416
Herb2 Meta Analysis Id
HBMA002416
Crd Id
CRD42021250425
Title
The effect of N-acetyl cysteine and vitamin E on oxidative status and blood parameters in transfusion dependent thalassemia patients: A systematic review and Network Meta-Analysis
Review Question
What is the effect of N-acetyl cysteine and vitamin E on oxidative status and blood parameters in transfusion dependent thalassemia patients?
Study Type Included
Clinical trials
Condition Being Studied
The oxidative status and blood parameters
Participant
Transfusion dependent thalassemia patients
Animal
Human Disease Modelled
Intervention
1-N-acetyl cysteine 2-vitamin E
Comparator Control
Control group (mainly placebo)
Main Outcome
oxidative status (total antioxidant capacity, ....), blood parameters (hemoglobin, ferritin level,...) Measures of effect mean & SD
Outcome Measure
Additional Outcome
Not applicable Measures of effect
Study Method
Meta-analysis, Systematic review
Keyword
Acetylcysteine; Blood Transfusion; Humans; Network Meta-Analysis; Oxidation-Reduction; Oxidative Stress; Thalassemia; Vitamin E
Contact
Sezaneh Haghpanah [email protected]
Organisational Affiliation
Shiraz University of Medical sciences
Funding Source
The study will be funded by Shiraz university of medical sciences
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Iran
Review Stage
Review Ongoing
First Submission Date
2021-04-21
Registration Date
2021-05-19
Anticipated Start Date
2021-04-14
Anticipated Completion Date
2021-05-31
Title Cn
N-乙酰半胱氨酸和维生素E对输血依赖性地中海贫血患者氧化状态和血液参数的影响:一项系统评价与网状Meta分析
Title En
The effect of N-acetyl cysteine and vitamin E on oxidative status and blood parameters in transfusion dependent thalassemia patients: A systematic review and Network Meta-Analysis
Bilingual Status
complete