Meta AnalysisID 2424
超声引导下经皮乙醇注射治疗甲状腺结节病变和颈部淋巴结转移
CRD42022338437
What is the safety, effectiveness and cost-effectiveness of percutaneous injection of ethanol guided ultrasonic thyroid nodular pathology and/or metastatic cervical adenopathies?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2424
- Evidence Id
- 10982
- Core Evidence Id
- 10982
- Source Meta Analysis Id
- 2373
- Herb2 Meta Analysis Id
- HBMA002373
- Crd Id
- CRD42022338437
- Title
- Percutaneous injection of ethanol guided ultrasonic in thyroid nodular pathology and metastatic cervical lymphadenopathy
- Review Question
- What is the safety, effectiveness and cost-effectiveness of percutaneous injection of ethanol guided ultrasonic thyroid nodular pathology and/or metastatic cervical adenopathies?
- Study Type Included
- Systematic reviews, Randomized clinical Trial, full economic evaluations.
- Condition Being Studied
- Nodular thyroid pathology and/or metastatic cervical adenopathies.
- Participant
- Inclusion: patients of any age with nodular thyroid pathology and/or metastatic cervical adenopathies Exclusion: patients with different pathology that nodular thyroid and/or metastatic cervical adenopathies
- Animal
- Human Disease Modelled
- Intervention
- Application of enolization (percutaneous injection of ethanol guided ultrasound) for the treatment of thyroid nodules or metastatic cervical adenopathies
- Comparator Control
- Usual care (surgery) or percutaneous thermal procedure (laser, radiofrequency or microwave ablation)
- Main Outcome
- Volume reduction rate (VRR ≥ 50%)
- Outcome Measure
- Additional Outcome
- Absence of Doppler signal in the treated nodule; Thyroglobulin < 1ng/dl in the puncture needle wash; Absence of neoplastic cellularity in puncture (Bethesda I); Mortality or survival; Adverse effects and complications (perceived pain, pressure discomfort, aesthetic, infection, total or partial loss of voice due to the involvement of the vocal cords, hypocalcemia); Recurrence of nodules; Malignancy of the nodules; Tolerability of the procedure; Levels of thyroglobulin, thyrotropin (TSH), thyroxine (T4) and triiodothyronine (T3), and blood calcium levels during the first 48 hours; Other clinical health outcomes: additional treatments; Patient self-perceived outcomes: health-related quality of life (HRQoL), other patient-reported outcomes (PROMs), or patient-reported experiences (PREMs). English Patient Reported Experience Measures); Socioeconomic effects (hospital stay, sick days); Cost and cost-effectiveness
- Study Method
- Cost effectiveness, Intervention, Systematic review
- Keyword
- Ethanol; Humans; Lymphadenopathy; Thyroid Nodule; Ultrasonics
- Contact
- Beatriz León Salas [email protected]
- Organisational Affiliation
- Evaluation Unit of Canary Island Health Service (SESCS) http://www.sescs.es
- Funding Source
- This work is supported by the Spanish Ministry of Health in the framework of the activities developed by the Spanish Network of Agencies for Health Technology Assessment for the National Health Service (RedETS)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Spain
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-06-08
- Registration Date
- 2022-06-19
- Anticipated Start Date
- 2022-03-15
- Anticipated Completion Date
- 2022-12-31
- Title Cn
- 超声引导下经皮乙醇注射治疗甲状腺结节病变和颈部淋巴结转移
- Title En
- Percutaneous injection of ethanol guided ultrasonic in thyroid nodular pathology and metastatic cervical lymphadenopathy
- Bilingual Status
- complete