Meta AnalysisID 2421
消融策略和Marshall静脉乙醇输注组样本量可能增加接受联合消融伴Marshall静脉乙醇输注治疗心房颤动患者的长期疗效：Meta分析
CRD42021277291
The long-term outcomes of ablation with vein of Marshall ethanol infusion (VOM-ABL) compared with ablation alone in patients with atrial fibrillation (AF) remains elusive. This meta-analysis aimed to compare the long-ter
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2421
- Evidence Id
- 10979
- Core Evidence Id
- 10979
- Source Meta Analysis Id
- 2370
- Herb2 Meta Analysis Id
- HBMA002370
- Crd Id
- CRD42021277291
- Title
- Ablation strategy and vein of Marshall ethanol infusion group sample size may increase the long-term efficacy in patients received combined ablation with vein of Marshall ethanol infusion for atrial fibrillation: a meta-analysis
- Review Question
- The long-term outcomes of ablation with vein of Marshall ethanol infusion (VOM-ABL) compared with ablation alone in patients with atrial fibrillation (AF) remains elusive. This meta-analysis aimed to compare the long-term outcome between VOM-ABL and ablation, and screen potential determinants for VOM-ABL procedure.
- Study Type Included
- randomized controlled trials and cohort, observational studies
- Condition Being Studied
- Radiofrequency ablation (RF) has been proven as an effective strategy for rhythm control in symptomatic and drug-refractory atrial fibrillation (AF) patients. Whereas, challenges still remain on AF ablation, including unsatisfied long-term successful rates, high risk of atrial tachycardia (AT) after AF ablation, and deficiency of atrial function. Preliminary study revealed that compared to ablation alone, ablation with VOM ethanol infusion (VOM-ABL) increased the likelihood of freedom from AF/AT for persistent AF. However, the long-term outcomes of VOM-ABL compared with ablation alone in AF patients remains elusive.
- Participant
- Inclusion criteria: (1) randomized controlled trials and cohort, observational studies, and case-control; (3) studies with a follow-up of 1 year or longer; (3) studies comparing the outcomes of VOM-ABL and ablation alone, including long-term freedom from AF/AT, long-term successful mitral isthmus (MI) block, pericardial effusion, stroke/transient ischemic attack (TIA), and all-cause death. (4) studies with full-text availability published in English in peer-reviewed journals. (5) for multiple publications of the same trial or cohort, only the study containing the most data was included. Exclusion criteria: single-arm study, studies without original data, review articles, case reports, letters, editorials, and animal studies were excluded
- Animal
- Human Disease Modelled
- Intervention
- Combined ablation with VOM ethanol infusion for atrial fibrillation
- Comparator Control
- Ablation alone for atrial fibrillation
- Main Outcome
- Studies comparing the outcomes of VOM-ABL and ablation alone, including long-term freedom from AF/AT, long-term successful mitral isthmus (MI) block, pericardial effusion, stroke/transient ischemic attack (TIA), and all-cause death. Measures of effect Relative risk (RR) and corresponding 95% confidence interval (CI) were calculated for each outcome in our study
- Outcome Measure
- Additional Outcome
- Study Method
- Intervention, Meta-analysis, Prognostic, Systematic review
- Keyword
- Atrial Fibrillation; Catheter Ablation; Ethanol; Humans; Pulmonary Veins; Sample Size
- Contact
- Feng Li [email protected]
- Organisational Affiliation
- Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China
- Funding Source
- Other Selection Criteria
- Final Publication
- Authors: Feng Li, MD#, Jin-Yu Sun, MD#, Li-Da Wu, MD#, Lei Zhang, MD, Qiang Qu, MD, Chao Wang, MD, Ling-Ling Qian, PhD, Ru-Xing Wang, MD, PhD* Title: The Long-Term Outcomes of Ablation With Vein of Marshall Ethanol Infusion vs. Ablation Alone in Patients With Atrial Fibrillation: A Meta-Analysis. Journal: Front Cardiovasc Med Front
- Same Topic Review
- Vein of Marshall; Ethanol effusion; Ablation; Atrial fibrillation; Meta-analysis
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Completed published
- First Submission Date
- 2021-09-06
- Registration Date
- 2021-10-07
- Anticipated Start Date
- 2021-09-06
- Anticipated Completion Date
- 2022-09-06
- Title Cn
- 消融策略和Marshall静脉乙醇输注组样本量可能增加接受联合消融伴Marshall静脉乙醇输注治疗心房颤动患者的长期疗效：Meta分析
- Title En
- Ablation strategy and vein of Marshall ethanol infusion group sample size may increase the long-term efficacy in patients received combined ablation with vein of Marshall ethanol infusion for atrial fibrillation: a meta-analysis
- Bilingual Status
- complete