Meta AnalysisID 2419
导管消融联合Marshall静脉乙醇输注与单纯导管消融对持续性心房颤动结局的比较：系统评价和Meta分析方案
CRD42021245278
The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of catheter ablation with vein of marshall ethanol Infusion for patients with persistent atrial fibrillation.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2419
- Evidence Id
- 10977
- Core Evidence Id
- 10977
- Source Meta Analysis Id
- 2369
- Herb2 Meta Analysis Id
- HBMA002369
- Crd Id
- CRD42021245278
- Title
- Comparison of Catheter Ablation With Vein of Marshall Ethanol Infusion and Catheter Ablation Alone on the Outcome of Persistent Atrial Fibrillation: Protocol for a Systematic Review and Meta-analysis
- Review Question
- The aim of this meta-analysis of randomized controlled trials is to evaluate the efficacy and safety of catheter ablation with vein of marshall ethanol Infusion for patients with persistent atrial fibrillation.
- Study Type Included
- Randomized controlled trials (RCTs) will be included.
- Condition Being Studied
- Ethanol infusion into the VOM has been considered a suitable adjuvant strategy for treating mitral flutter after failed endocardial ablation, as well as perimitral flutter (mitral flutter with epicardial connections) generated following pulmonary vein isolation (PVI) or mitral valve surgery. The VOM has gained prominence as a therapeutic target because of its unique anatomical location by connecting the coronary sinus (CS) with the pulmonary veins (PVs), the VOM promotes autonomic arrhythmogenesis. However, the efficacy of VOM ethanol infusion has not been evaluated systematically.
- Participant
- Adults with persistent atrial fibrillation (as diagnosed by a clinician, or using any recognized diagnostic criteria) will be included.
- Animal
- Human Disease Modelled
- Intervention
- Catheter ablation combined with vein of marshall ethanol Infusion was the main intervention
- Comparator Control
- Catheter Ablation Alone for patients with persistent atrial fibrillation
- Main Outcome
- Recurrence rate of atrial tachyarrhythmias after catheter ablation combine with vein of marshall ethanol Infusion. Measures of effect Odds ratio (OR) with 95% confdence intervals (CIs)
- Outcome Measure
- Additional Outcome
- Clinical complications of catheter ablation Measures of effect Odds ratio (OR) with 95% confdence intervals (CIs)
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Atrial Fibrillation; Catheter Ablation; Ethanol; Humans; Pulmonary Veins
- Contact
- Jin-yi Li [email protected]
- Organisational Affiliation
- Affiliated Hospital of Guilin Medical University
- Funding Source
- General Program of Natural Science Foundation of Guangxi Province of China Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> (Grant No. 2017GXNSFAA198129)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-03-26
- Registration Date
- 2021-04-23
- Anticipated Start Date
- 2021-03-30
- Anticipated Completion Date
- 2021-12-31
- Title Cn
- 导管消融联合Marshall静脉乙醇输注与单纯导管消融对持续性心房颤动结局的比较：系统评价和Meta分析方案
- Title En
- Comparison of Catheter Ablation With Vein of Marshall Ethanol Infusion and Catheter Ablation Alone on the Outcome of Persistent Atrial Fibrillation: Protocol for a Systematic Review and Meta-analysis
- Bilingual Status
- complete