Meta AnalysisID 2416
无合并症男性中乙醇摄入与胰岛素敏感性代谢的关系：系统评价
CRD42020205107
Could the alcohol intake enhance the insulin sensitivity in men between 15 and 60 years with no comorbidities?
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Record Fields
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- Meta Analysis Id
- 2416
- Evidence Id
- 10974
- Core Evidence Id
- 10974
- Source Meta Analysis Id
- 2366
- Herb2 Meta Analysis Id
- HBMA002366
- Crd Id
- CRD42020205107
- Title
- Relationship between ethanol intake and insulin sensitivity metabolism in men with no comorbidities: A systematic review
- Review Question
- Could the alcohol intake enhance the insulin sensitivity in men between 15 and 60 years with no comorbidities?
- Study Type Included
- Primary quantitative studies or mixed methods studies with a quantitative component (using descriptive or inferential statistics methods, with parametric or non-parametric methods), reporting dosage or timing of alcohol intake, and insulin profile. Conference abstracts, and studies focused on treatment of alcohol dependence or without biochemical parameters will be excluded.
- Condition Being Studied
- Ethanol ranks first on the list of abused drugs in many parts of the world. Alcohol intake is a chronic disorder, with psychological and physical addiction that affects around 10% of the world population. It has been reported that alcohol abuse and dependency occupy third place in the risks to human health in the world, where Latin American countries and those belonging to the former Soviet Union represent more than double the risk for alcohol consumption than the global average.
- Participant
- Inclusion and exclusion criteria has been described according to the PICO principles. Men aged between 15 and 60 years old, living in the community; including healthy participants with no pre-conditions for later ill health such as high blood pressure, high cholesterol, overweight or obese, impaired cognitive function and functional limitations. People over 60 years old were excluded to present frequently chronic diseases. In addition, people on medication or studies that primarily focused on populations with ill health e.g. stroke, coronary heart disease, mental health conditions will be excluded.
- Animal
- Human Disease Modelled
- Intervention
- Epidemiological evidence has shown beneficial effects to alcohol consumption when any kind of alcoholic beverage it is drinking from light-to-moderate, showing a reduction in mortality, due primarily to a reduced risk of coronary heart disease. It is not clear how ethanol affects those parameters; however, some studies suggest that light-to-moderate drinking of alcohol improving insulin sensitivity. This condition is characterized by relatively low plasma insulin levels, which are paradoxically effective enough to increase glucose uptake and to improve the profile of plasma lipids and lipoproteins.
- Comparator Control
- Non-exposed control group.
- Main Outcome
- To evaluate the relationship between ethanol intake and insulin sensitivity metabolism in men with no comorbidities. The variables are: dosage or timing of alcohol intake, insulin profile and health parameters, such biochemical and metabolic analysis. Measures of effect odds ratios p value
- Outcome Measure
- Additional Outcome
- None Measures of effect None
- Study Method
- Systematic review
- Keyword
- Blood Glucose; Ethanol; Humans; Insulin; Insulin Resistance; Male
- Contact
- Cristian Sandoval [email protected]
- Organisational Affiliation
- Universidad de La Frontera
- Funding Source
- Universidad de La Frontera Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> DI20-0003
- Other Selection Criteria
- Final Publication
- http://www.intjmorphol.com/wp-content/uploads/2021/06/art_27_393.pdf
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Chile
- Review Stage
- Review Completed published
- First Submission Date
- 2020-08-19
- Registration Date
- 2020-09-18
- Anticipated Start Date
- 2020-08-30
- Anticipated Completion Date
- 2020-09-30
- Title Cn
- 无合并症男性中乙醇摄入与胰岛素敏感性代谢的关系：系统评价
- Title En
- Relationship between ethanol intake and insulin sensitivity metabolism in men with no comorbidities: A systematic review
- Bilingual Status
- complete