Meta AnalysisID 24
补充瓜拉那对自主神经系统的影响：一项系统评价
CRD42021273118
Which are the effects of guarana supplementation on the autonomic nervous system?
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Record Fields
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- Meta Analysis Id
- 24
- Evidence Id
- 8582
- Core Evidence Id
- 8582
- Source Meta Analysis Id
- 22
- Herb2 Meta Analysis Id
- HBMA000022
- Crd Id
- CRD42021273118
- Title
- Effects of Guarana Supplementation on the Autonomic Nervous System – A Systematic Review
- Review Question
- Which are the effects of guarana supplementation on the autonomic nervous system?
- Study Type Included
- We will include randomised or non-randomized trials to assess the beneficial effects of the treatments, crossover, single or double blind, and placebo-controlled clinical trials.
- Condition Being Studied
- Cardiovascular diseases from changes in heart rate variability (HRV). Guarana and exercise can help prevent these diseases in adults
- Participant
- Inclusion: Adults, men and women (between 18 and 45 years old) in good health and free from illicit drugs and without prescription drugs. Exclusion: Elderlies, adolescents, pregnant women, regular smokers, severe physical illnesses, psychiatric disorders (including depression and anxiety) or neurological disease, metabolic, endocrine and cardiac disorders, chronic alcohol consumption, as well as use of psychotropic drugs or medications that affect the cardiovascular system.
- Animal
- Human Disease Modelled
- Intervention
- The ingestion of an effervescent drink or capsule containing guarana and may be a session of physical exercise. The type of physical exercise has not been established.
- Comparator Control
- Placebo, such as drinks and effervescent tablets, capsules and water added with unsweetened syrup.
- Main Outcome
- The results will be presented through the assessment of acute behavioral and mood effects, cognitive performance, heart rate variability, acute cerebral electrophysiological changes and potential psychoactive effects. Measures of effect HRV will be evaluated in the time domain (RMSSD - square root of the mean square of the differences between cardiac intervals) and in the frequency domain (HF - high frequency, ranging from 0.15 to 0.4Hz).
- Outcome Measure
- Additional Outcome
- Maximum oxygen consumption before and after the intervention
- Study Method
- Systematic review
- Keyword
- Autonomic Nervous System; Caffeine; Dietary Supplements; Humans; Paullinia; Plant Extracts
- Contact
- Isabela De Pretto Mansano [email protected]
- Organisational Affiliation
- Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) https://www2.unesp.br/
- Funding Source
- There were no funders for this review
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English, Portuguese-Brazil
- Country
- Brazil
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-09-10
- Registration Date
- 2021-10-11
- Anticipated Start Date
- 2020-09-14
- Anticipated Completion Date
- 2021-11-08
- Title Cn
- 补充瓜拉那对自主神经系统的影响：一项系统评价
- Title En
- Effects of Guarana Supplementation on the Autonomic Nervous System – A Systematic Review
- Bilingual Status
- complete