Meta AnalysisID 2397
表没食子儿茶素没食子酸酯对成人血脂、血压和肥胖的影响：一项系统评价与Meta分析
CRD42023391478
People：people with different disease or healthy people. Interventions：epigallocatechin gallate. Control measures: placebo or no treatment. Outcome indicators: weight , diastolic pressure, systolic pressure, Total serum c
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2397
- Evidence Id
- 10955
- Core Evidence Id
- 10955
- Source Meta Analysis Id
- 2345
- Herb2 Meta Analysis Id
- HBMA002345
- Crd Id
- CRD42023391478
- Title
- Effect of epigallocatechin gallate on adult blood lipids, blood pressure and obesity: a systematic evaluation and meta-analysis
- Review Question
- People：people with different disease or healthy people. Interventions：epigallocatechin gallate. Control measures: placebo or no treatment. Outcome indicators: weight , diastolic pressure, systolic pressure, Total serum cholesterol (TC), low density lipoprotein (LDL), triglyceride (TG).
- Study Type Included
- Randomized clinical trial，excluding animal experiments.
- Condition Being Studied
- Obesity, hypertension and hyperlipidemia are high risk factors of many diseases and are major public health events in the world. Green tea, green tea extract, catechin and epigallocatechin gallate have good effects on many diseases. The purpose of this systematic evaluation is to evaluate the effect of epigallocatechin gallate on obesity, blood pressure and blood lipids.
- Participant
- People with different disease or healthy people
- Animal
- Human Disease Modelled
- Intervention
- epigallocatechin gallate
- Comparator Control
- Placebo or no treatment
- Main Outcome
- Mean and standard deviation of serum cholesterol, low density lipoprotein and triglyceride concentrations , body weight, systolic and diastolic blood pressure. Measures of effect Use R language for meta-analysis. Heterogeneity was determined using I² statistics and the Cochran Q test.If the fixed effect model is used for homogeneity, the random effect model is used for heterogeneity. For the change of main outcome indicators, we use WMD as the effect quantity. With regard to the sources of heterogeneity, we intend to use subgroup analysis for detection. Considering the meta-regression, we used this method to explore the impact of intervention duration on the heterogeneity of the main outcome indicators. Finally, we test the existence of publication bias through funnel diagram, Egger method and Begg method. At the same time, we will also use sensitivity analysis to check the reliability of the research results.
- Outcome Measure
- Additional Outcome
- NO Measures of effect NO
- Study Method
- Systematic review
- Keyword
- Adult; Blood Pressure; Catechin; Humans; Lipids; Triglycerides; epigallocatechin gallate
- Contact
- Tao Zhong [email protected]
- Organisational Affiliation
- Hebei Medical University https://www.hebmu.edu.cn
- Funding Source
- NO
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2023-01-13
- Registration Date
- 2023-01-23
- Anticipated Start Date
- 2023-01-31
- Anticipated Completion Date
- 2023-05-31
- Title Cn
- 表没食子儿茶素没食子酸酯对成人血脂、血压和肥胖的影响：一项系统评价与Meta分析
- Title En
- Effect of epigallocatechin gallate on adult blood lipids, blood pressure and obesity: a systematic evaluation and meta-analysis
- Bilingual Status
- complete