Meta AnalysisID 2386
木脂素和肠内酯对乳腺癌女性生存的影响：Meta分析
CRD42020208054
The purpose of this meta-analysis is to evaluate the impact of lignan and its products enterolactone on the survival of breast cancer patients.
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2386
- Evidence Id
- 10944
- Core Evidence Id
- 10944
- Source Meta Analysis Id
- 2334
- Herb2 Meta Analysis Id
- HBMA002334
- Crd Id
- CRD42020208054
- Title
- Lignan and Enterolactone and Survival in Women with Breast Cancer: A Meta-Analysis
- Review Question
- The purpose of this meta-analysis is to evaluate the impact of lignan and its products enterolactone on the survival of breast cancer patients.
- Study Type Included
- Cohort study or case-control study or cross-sectional study
- Condition Being Studied
- Although many risk and prognostic factors of breast cancer have been established, and numerous biomarkers have been linked to breast cancer, our understanding of breast cancer prognosis is still evolving. Phytoestrogens are a large group of plant-derived compounds and contain a phenolic ring which allows them to bind to the oestrogen receptor (ER), showing weak oestrogenic activity. Lignan is a kind of phytoestrogens, and its relationship with the prognosis of breast cancer deserves our attention.
- Participant
- We use the following criteria: 1) research conducted in women diagnosed with breast cancer, 2) report lignan intake or serum enterolactone(either before or after diagnosis) as exposure, 3) report all causes or Breast cancer-specific mortality as the result of interest, and 4) provide an estimate of the effect as a relative risk (RR) or hazard ratio, and a 95% confidence interval (CI) for the corresponding mortality.
- Animal
- Human Disease Modelled
- Intervention
- lignan intake or serum enterolactone(either before or after diagnosis) as exposure
- Comparator Control
- Comparison of high lignin intake and low lignin intake
- Main Outcome
- all causes or Breast cancer-specific mortality Measures of effect Relative risk
- Outcome Measure
- Additional Outcome
- None Measures of effect none
- Study Method
- Meta-analysis, Systematic review
- Keyword
- 2,3-bis(3'-hydroxybenzyl)butyrolactone; 4-Butyrolactone; Breast Neoplasms; Female; Humans; Lignans
- Contact
- Liu zhen [email protected]
- Organisational Affiliation
- Nanjing Medical University, Nanjing City, Jiangsu Province, China
- Funding Source
- no
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-09-07
- Registration Date
- 2020-10-09
- Anticipated Start Date
- 2020-09-07
- Anticipated Completion Date
- 2020-10-31
- Title Cn
- 木脂素和肠内酯对乳腺癌女性生存的影响：Meta分析
- Title En
- Lignan and Enterolactone and Survival in Women with Breast Cancer: A Meta-Analysis
- Bilingual Status
- complete