Meta AnalysisID 2342

间苯三酚联合孕激素治疗先兆流产:一项系统评价与Meta分析

CRD42020214967

To assess the efficacy of phloroglucinol and progestins combination treatment for threatened miscarriage.

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Record Fields

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Meta Analysis Id
2342
Evidence Id
10900
Core Evidence Id
10900
Source Meta Analysis Id
2289
Herb2 Meta Analysis Id
HBMA002289
Crd Id
CRD42020214967
Title
Phloroglucinol and progestins combination treatment for threatened miscarriage: a systematic review and meta-analysis
Review Question
To assess the efficacy of phloroglucinol and progestins combination treatment for threatened miscarriage.
Study Type Included
2We will include randomise controlled trials to assess the effects of the treament.
Condition Being Studied
Pergnancy and childbirth
Participant
All pregnant women who present with vaginal bleeding during the first 20 weeks' gestaion, with or without lower abdominal pain, while the cervix is closed and the fetus is viable.
Animal
Human Disease Modelled
Intervention
The intervention is intramuscular injection of phloroglucinol combined with progestins.
Comparator Control
The comparators are traditional treatments with progestins .
Main Outcome
The total effective rate (TER) (i.e., effectual, uterine contractions were obviously relieved or disappeared within 12 hours of medication; improved, uterine contractions were relieved to a certain degree within 24 hours of medication; and ineffective, symptoms showed no change or were even aggravated within 48 hours of medication); the total effective rate = (number of effectual cases + number of improved cases)/number of total cases × 100% Measures of effect Relative risks.
Outcome Measure
Additional Outcome
The rate of adverse reactions (oedema, hyperkalaemia, hypernatraemia, hypertension). The duration of symptons. The level of secrum P. Measures of effect Weighted Mean Difference
Study Method
Meta-analysis, Systematic review
Keyword
Abortion, Threatened; Female; Humans; Phloroglucinol; Progestins
Contact
Tianyu Shi [email protected]
Organisational Affiliation
Nantong University
Funding Source
None.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2020-10-20
Registration Date
2020-11-20
Anticipated Start Date
2020-10-31
Anticipated Completion Date
2021-03-24
Title Cn
间苯三酚联合孕激素治疗先兆流产:一项系统评价与Meta分析
Title En
Phloroglucinol and progestins combination treatment for threatened miscarriage: a systematic review and meta-analysis
Bilingual Status
complete