Meta AnalysisID 2337

间苯三酚治疗妇产科源性腹部或盆腔疼痛的疗效:对随机对照试验文献的系统评价

CRD42018094065

Is there good evidence to justify the prescription of drugs containing phloroglucinol to treat abdominal or pelvic pain of gynecologic or obstetrical origin?

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Record Fields

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Meta Analysis Id
2337
Evidence Id
10895
Core Evidence Id
10895
Source Meta Analysis Id
2285
Herb2 Meta Analysis Id
HBMA002285
Crd Id
CRD42018094065
Title
Efficacy of phloroglucinol for the treatment of abdominal or pelvic pain of gynecologic or obstetrical origin: a systematic review of litterature of randomised, controlled trials<br />
Review Question
Is there good evidence to justify the prescription of drugs containing phloroglucinol to treat abdominal or pelvic pain of gynecologic or obstetrical origin?
Study Type Included
We will include randomised and controlled versus placebo trials to assess the beneficial effects of the treatments. We will exclude articles for which the full-text is not available either in English or in French. We will exclude trials which concern pain caused by digestive or renal or metabolic or traumatic pathologies.
Condition Being Studied
Abdominal and pelvic pain caused by gynecologic or obstetric pathologies or cases.
Participant
Inclusion: Female patients without restriction of age or ethnic group. Exclusion: male patients or mixed gender studies.
Animal
Human Disease Modelled
Intervention
Administration of phloroglucinol to treat abdominal or pelvic pain caused by a gynecologic or obstetric pathology or state. In hospital or in out-patient care setting. No matter the form of administration (oral administration or injection).
Comparator Control
Administration of placebo.
Main Outcome
Pain relief from baseline to end of trial with a binary response pattern: yes or no. No matter the tool used to measure this, we will use the author's definition of responsivenss to treatment when available in the metholodology section of the article. Measures of effect From baseline to end of trial.
Outcome Measure
Additional Outcome
If applicable, we will analyse pain relief as a continuous outcome (from baseline to end of trial) by comparison of standard mean difference or mean difference (if all trials use the same means to measure pain relief). Measures of effect From baseline to end of trial.
Study Method
Systematic review
Keyword
Abdomen; Female; Humans; Obstetrics; Pelvic Pain; Phloroglucinol
Contact
Clara Blanchard [email protected]
Organisational Affiliation
Département de Médecine Générale, Faculté de Médecine de Poitiers http://medphar.univ-poitiers.fr/acces-rapides/departement-de-medecine-generale--1189521.kjsp
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
We previously published a review analysing the efficacy of phloroglucinol for abdominal pain and excluded the trials concerning gynecology or obstetrics. Eur J Clin Pharmacol. 2018 May;74(5):541-548. doi: 10.1007/s00228-018-2416-6. Epub 2018 Jan 19. Blanchard C, Pouchain D, Vanderkam P, Perault-Pochat MC, Boussageon R, Vaillant-Roussel H.
Published Protocol
Review Type
Language
English
Country
France
Review Stage
Review Completed not published
First Submission Date
2018-04-19
Registration Date
2018-05-04
Anticipated Start Date
2018-04-22
Anticipated Completion Date
2018-08-31
Title Cn
间苯三酚治疗妇产科源性腹部或盆腔疼痛的疗效:对随机对照试验文献的系统评价
Title En
Efficacy of phloroglucinol for the treatment of abdominal or pelvic pain of gynecologic or obstetrical origin: a systematic review of litterature of randomised, controlled trials<br />
Bilingual Status
complete