Meta AnalysisID 2320

双氢青蒿素-哌喹在流行国家治疗无并发症间日疟的疗效:一项Meta分析与试验序贯分析

CRD42018100327

What is the efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium vivax malaria in endemic countries?

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Record Fields

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Meta Analysis Id
2320
Evidence Id
10878
Core Evidence Id
10878
Source Meta Analysis Id
2269
Herb2 Meta Analysis Id
HBMA002269
Crd Id
CRD42018100327
Title
Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated plasmodium vivax malaria in endemic countries: a meta-analysis and trial sequential analysis
Review Question
What is the efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium vivax malaria in endemic countries?
Study Type Included
Randomized Control Trials
Condition Being Studied
Vivax Malaria
Participant
Participants (P): Plasmodium vivax infected patients
Animal
Human Disease Modelled
Intervention
Intervention (I): Dihydroartemisinin (DHP)-Piperaquine (PPQ) combination therapy
Comparator Control
Comparator (C): Alternative ACT or placebo
Main Outcome
PCR confirmed treatment success  Measures of effect at day 28 at day 42/63
Outcome Measure
Additional Outcome
Adverse events/ serious adverse events  Measures of effect at any follow up time
Study Method
Intervention, Meta-analysis
Keyword
Artemisinins; Humans; Malaria, Vivax; Quinolines; dihydroartemisinin; piperaquine
Contact
Htet Htet [email protected]
Organisational Affiliation
International Medical University http://www.imu.edu.my/imu/
Funding Source
International Medical University 
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Malaysia
Review Stage
Review Ongoing
First Submission Date
2018-06-25
Registration Date
2018-08-13
Anticipated Start Date
2018-06-01
Anticipated Completion Date
2018-12-31
Title Cn
双氢青蒿素-哌喹在流行国家治疗无并发症间日疟的疗效:一项Meta分析与试验序贯分析
Title En
Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated plasmodium vivax malaria in endemic countries: a meta-analysis and trial sequential analysis
Bilingual Status
complete