Meta AnalysisID 2301
淀粉酶和脂肪酶在诊断腹部创伤胰腺损伤中的价值：系统评价
CRD42022336096
This review aims to answer the following questions: 1. Following trauma, when do the enzymes (amylase and lipase) rise? 2. How do the enzyme levels correlate with the CT findings? 3. Do the enzyme levels correlate with t
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Record Fields
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- Meta Analysis Id
- 2301
- Evidence Id
- 10859
- Core Evidence Id
- 10859
- Source Meta Analysis Id
- 2248
- Herb2 Meta Analysis Id
- HBMA002248
- Crd Id
- CRD42022336096
- Title
- A systematic review of the utility of amylase and lipase in diagnosing pancreas injury in abdominal trauma
- Review Question
- This review aims to answer the following questions: 1. Following trauma, when do the enzymes (amylase and lipase) rise? 2. How do the enzyme levels correlate with the CT findings? 3. Do the enzyme levels correlate with trauma to other organs? 4. Do the enzyme levels correlate with clinical outcomes? 5. Ultimately, how useful are amylase and lipase for clinical decision-making at the initial presentation with abdominal trauma?
- Study Type Included
- All commentaries, case reports, conference abstracts, literature overviews, secondary analyses for previously published articles and non-English studies will be excluded.
- Condition Being Studied
- Traumatic pancreatic injury.
- Participant
- Inclusion criteria: Adult patients (age ≥18). Exclusion criteria: Pediatric patients (age <18).
- Animal
- Human Disease Modelled
- Intervention
- Inclusion criteria: Articles describing blunt/penetrating abdominal injury in adult patients; Articles reporting serum amylase and lipase measurements for the study population.
- Comparator Control
- None.
- Main Outcome
- Mortality. Measures of effect Not applicable.
- Outcome Measure
- Additional Outcome
- Morbidity, ICU admissions, length of hospital stay, referral to tertiary pancreatic unit and the need for endoscopic or operative intervention. Measures of effect Not applicable.
- Study Method
- Diagnostic, Prognostic, Systematic review
- Keyword
- Abdomen; Abdominal Injuries; Adult; Amylases; Biomarkers; Clinical Decision-Making; Diagnostic Techniques, Digestive System; Digestive System Surgical Procedures; Humans; Lipase; Mortality; Pancreas; Pancreatitis; Prognosis; Wounds and Injuries
- Contact
- Ikemsinachi Nzenwa [email protected]
- Organisational Affiliation
- University of Liverpool School of Medicine
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-06-16
- Registration Date
- 2022-07-08
- Anticipated Start Date
- 2022-07-17
- Anticipated Completion Date
- 2022-08-31
- Title Cn
- 淀粉酶和脂肪酶在诊断腹部创伤胰腺损伤中的价值：系统评价
- Title En
- A systematic review of the utility of amylase and lipase in diagnosing pancreas injury in abdominal trauma
- Bilingual Status
- complete