Meta AnalysisID 2298

唾液α-淀粉酶抑制剂作为龋病保护剂的作用——系统文献综述

CRD42021229908

Do salivary alpha-amylase inhibitors have a role as protective agents in dental caries?

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Record Fields

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Meta Analysis Id
2298
Evidence Id
10856
Core Evidence Id
10856
Source Meta Analysis Id
2245
Herb2 Meta Analysis Id
HBMA002245
Crd Id
CRD42021229908
Title
Role of Salivary α-amylase inhibitors as Protective Agents in Caries - Systematic Literature Review
Review Question
Do salivary alpha-amylase inhibitors have a role as protective agents in dental caries?
Study Type Included
Primary experimental studies, in vitro and in vivo.
Condition Being Studied
Dental caries. Use of salivary alpha amylase inhibitors for the prevention and management of caries
Participant
In vitro studies in caries models, and in vivo and in situ studies developed in humans and animals.
Animal
Human Disease Modelled
Intervention
Studies where the intervention is carried out with natural or pharmacological salivary alpha amylase inhibitors.
Comparator Control
Studies where there is a control group for the intervention.
Main Outcome
Streptococcus mutans levels Salivary alpha-amylase Demineralization of dental hard tissues Measures of effect Microbiological variables: Streptococcus mutans levels by measuring colony-forming units Salivary alpha-amylase: Salivary alpha-amylase level, test kit Demineralization of dental hard tissues: Surface or transverse hardness loss
Outcome Measure
Additional Outcome
N/A Measures of effect N/A
Study Method
Meta-analysis, Systematic review
Keyword
Dental Caries Susceptibility; Humans; Protective Agents; Saliva; alpha-Amylases
Contact
Rodrigo A Giacaman [email protected]
Organisational Affiliation
University of Talca www.utalca.cl
Funding Source
Internal funds from the Department of Oral Rehabilitation, University of Talca, Chile Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> N/A
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Chile
Review Stage
Review Ongoing
First Submission Date
2021-01-12
Registration Date
2021-02-12
Anticipated Start Date
2020-07-17
Anticipated Completion Date
2021-04-02
Title Cn
唾液α-淀粉酶抑制剂作为龋病保护剂的作用——系统文献综述
Title En
Role of Salivary α-amylase inhibitors as Protective Agents in Caries - Systematic Literature Review
Bilingual Status
complete