Meta AnalysisID 2297
糖尿病中的唾液淀粉酶生物标志物
CRD42021227436
How does salivary amylase levels impact on diagnose of diabetes mellitus compared to glycaemic blood levels?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2297
- Evidence Id
- 10855
- Core Evidence Id
- 10855
- Source Meta Analysis Id
- 2244
- Herb2 Meta Analysis Id
- HBMA002244
- Crd Id
- CRD42021227436
- Title
- Salivary amylase biomarkers in diabetes
- Review Question
- How does salivary amylase levels impact on diagnose of diabetes mellitus compared to glycaemic blood levels?
- Study Type Included
- The inclusion criteria were randomized controlled clinical trials (RCCTs),
- Condition Being Studied
- Diabetes mellitus
- Participant
- Adults with diabetes mellitus (as diagnosed using any recognised diagnostic criteria).
- Animal
- Human Disease Modelled
- Intervention
- with diabetes in humans without exclude of reason of age, sex, or race. Any type of comparison between interventions was considered as valid, as long as one of them consisted in the prescription and application of biomarker diagnostic method, as the case of salivary marker or amylase and blood parameters as the case of glycated haemoglobin or glucose levels .
- Comparator Control
- The use of another design methods research was not a reason for exclusion, although this was taken into account in the analysis of the data.
- Main Outcome
- studies in patients with diabetes in humans without exclude of reason of age, sex, or race. Any type of comparison between amylase and DM diagnose was considered as valid, as long as one of them consisted in the prescription and application of biomarker diagnostic method, as the case of salivary marker or amylase and blood parameters as the case of glycated haemoglobin or glucose levels Measures of effect Reasons for exclusion were those studies which did not surpass the eligibility criteria described and/or whose level of methodological quality was doubtful. The risk of bias assessment in the studies was carried out using the tool Review Manager (RevMan) of The Cochrane Library, v.5.3. Likewise, any study selected could have been omitted from the review if, during the data extraction, information had been found which justified its exclusion, such as, in the end, not fulfilling the inclusion criteria defined, or if there were suspicions about the methodological quality used, among others. Studies in which the participants did not have diabetes melitus disease were excluded, as well as those which did not use salivary diagnose.
- Outcome Measure
- Additional Outcome
- None Measures of effect After obtaining them, a complete reading was carried out, again independently, of the documents selected by each of the previous reviewers. In the complete reading, we valued a new their eligibility according to the strict fulfilment of the inclusion criteria originally described, which was necessary for the study to be finally selected for review.
- Study Method
- Systematic review
- Keyword
- Biomarkers; Diabetes Mellitus; Humans; Saliva; alpha-Amylases
- Contact
- Emmnanuel Navarro-Flores [email protected]
- Organisational Affiliation
- University of Valencia https://www.uv.es/uvweb/servicio-investigacion/es/ciencias-salud/grupo-1285949713561.html?p2=GIUV2017-398
- Funding Source
- Universitat de València.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Spain
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-12-21
- Registration Date
- 2021-01-21
- Anticipated Start Date
- 2020-10-08
- Anticipated Completion Date
- 2021-01-28
- Title Cn
- 糖尿病中的唾液淀粉酶生物标志物
- Title En
- Salivary amylase biomarkers in diabetes
- Bilingual Status
- complete