Meta AnalysisID 2292
胰切除术后引流液胰淀粉酶诊断胰漏 [Cochrane方案]
CRD42016043860
To determine the diagnostic accuracy of pancreatic amylase in drain fluid for the diagnosis of pancreatic leak in patients who had undergone pancreatic resection. Secondary objectives:If we identify heterogeneity, we pla
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Record Fields
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- Meta Analysis Id
- 2292
- Evidence Id
- 10850
- Core Evidence Id
- 10850
- Source Meta Analysis Id
- 2238
- Herb2 Meta Analysis Id
- HBMA002238
- Crd Id
- CRD42016043860
- Title
- Pancreatic amylase in drain fluid for the diagnosis of pancreatic leak in post pancreatic resection [Cochrane Protocol]
- Review Question
- To determine the diagnostic accuracy of pancreatic amylase in drain fluid for the diagnosis of pancreatic leak in patients who had undergone pancreatic resection. Secondary objectives:If we identify heterogeneity, we plan to explore the following potential sources of heterogeneity: risk of bias, publication status, prospective or retrospective studies, type of pancreatic resection (pancreatoduodenectomies versus distal pancreatic resection), different aetiologies, and different reference standards.
- Study Type Included
- We will include all studies that evaluate the diagnostic test accuracy of pancreatic amylase in the drain fluid for the diagnosis of pancreatic leak in patients who had undergone pancreatic resection. To be included, studies must provide information on the index test and reference standards irrespective of language or publication status, or whether the data is collected prospectively or retrospectively. However, we will exclude case reports that describe how the diagnosis of pancreatic fistula was made on an individual patient or a group of patients and which do not provide sufficient diagnostic test accuracy data, i.e. true positive, false positive, false negative, and true negative. We will also exclude case-control studies because these studies are prone to bias (Whiting 2011).
- Condition Being Studied
- Clinically significant post-operative pancreatic leak or fistula (ISGPF Grade B or Grade C fistula)
- Participant
- Patients who have undergone pancreatic resection with drain fluid at least 48 hours after pancreatic resection irrespective of the volume of the drain fluid.
- Animal
- Human Disease Modelled
- Intervention
- Drain fluid pancreatic amylase.
- Comparator Control
- Reference standards.
- Main Outcome
- Diagnostic test accuracy.
- Outcome Measure
- Additional Outcome
- None.
- Study Method
- Diagnostic, Systematic review
- Keyword
- Amylases; Diagnostic Techniques and Procedures; Diagnostic Techniques, Digestive System; Drainage; Humans; Pancreas; Postoperative Care; Postoperative Complications; Postoperative Period
- Contact
- Kurinchi Selvan Gurusamy [email protected]
- Organisational Affiliation
- The Cochrane Collaboration http://www.cochrane.org/
- Funding Source
- None specified
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- England
- Review Stage
- Review Ongoing
- First Submission Date
- Registration Date
- 2016-07-29
- Anticipated Start Date
- 2015-12-15
- Anticipated Completion Date
- 2017-12-15
- Title Cn
- 胰切除术后引流液胰淀粉酶诊断胰漏 [Cochrane方案]
- Title En
- Pancreatic amylase in drain fluid for the diagnosis of pancreatic leak in post pancreatic resection [Cochrane Protocol]
- Bilingual Status
- complete