Meta AnalysisID 2203
大豆异黄酮摄入与胃癌风险：Meta分析
CRD42020161526
To find out whether the intake of soybean isoflavones will affect the risk of gastric cancer
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Record Fields
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- Meta Analysis Id
- 2203
- Evidence Id
- 10761
- Core Evidence Id
- 10761
- Source Meta Analysis Id
- 2154
- Herb2 Meta Analysis Id
- HBMA002154
- Crd Id
- CRD42020161526
- Title
- Soy isoflavones consumption and gastric cancer risk:a meta-analysis
- Review Question
- To find out whether the intake of soybean isoflavones will affect the risk of gastric cancer
- Study Type Included
- Included criteria: ①study used an observational design; ②human trials that evaluated the association between soy isoflavones consumption and gastric cancer risk; ③the risk point estimate was reported as OR or RR with 95% confidence interval or study provided enough data that OR or RR could be calculated. Exclusion criteria: ①cell studies and animal studies; ②abstracts, reviews, letters to the editors, case reports; ③data related to exposure assessed (blood/ urinary levels); ④studies without sufficient data to estimate the OR or RR with 95% confidence interval.
- Condition Being Studied
- Gastric cancer is one of the most common malignant tumors in the world, ranking the 4th and 5th respectively in men and women with an estimated 951, 600 new cases and also the 3rd and 5th lethal cancer cause in men and women with total 723, 100 deaths worldwide in 2012.
- Participant
- No restrictions.
- Animal
- Human Disease Modelled
- Intervention
- The exposure assessed was dietary intake of soy or isoflavone. Nine food items for soy products [miso soup, tofu( soy bean curd), deep-fried tofu, fried tofu, freeze-dried tofu, natto, houbamiso, soymilk and boiled soy beans] were included. Soy consumption was expressed as milligrams of soy isoflavones intake per day. Isoflavones include genistein, daidzein and glycitein.
- Comparator Control
- Take the lowest soy isoflavone intake group as the control group.
- Main Outcome
- The main outcome is gastric cancer. Cancer incidence was mainly confirmed through regional population-based cancer registries. Measures of effect The causes of cancer were coded according to the International Classification of Diseases and Health Related Problems, 10th Revision (ICD-10). Gastric cancer was defined as code C16.As for cases that were recognized by death certificates, the cancer registries made a backward tracking review of cancer incidence and determined the patients' incidence date based on the description in the death certificate.
- Outcome Measure
- Additional Outcome
- None Measures of effect Not applicable
- Study Method
- Epidemiologic, Meta-analysis, Systematic review
- Keyword
- Humans
- Contact
- wang yameng [email protected]
- Organisational Affiliation
- Zhengzhou University
- Funding Source
- Science and technology public project of Henan Province
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-12-08
- Registration Date
- 2020-04-28
- Anticipated Start Date
- 2019-12-02
- Anticipated Completion Date
- 2020-05-01
- Title Cn
- 大豆异黄酮摄入与胃癌风险：Meta分析
- Title En
- Soy isoflavones consumption and gastric cancer risk:a meta-analysis
- Bilingual Status
- complete