Meta AnalysisID 2198
金雀花碱用于戒烟的有效性、安全性和成本效果：系统评价与Meta分析
CRD42021266448
Is cytisine effective, safe and cost-effective for smoking cessation among adult smokers?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2198
- Evidence Id
- 10756
- Core Evidence Id
- 10756
- Source Meta Analysis Id
- 2146
- Herb2 Meta Analysis Id
- HBMA002146
- Crd Id
- CRD42021266448
- Title
- The efficacy, safety and cost effectiveness of Cytisine for smoking cessation: a systematic review and meta-analysis
- Review Question
- Is cytisine effective, safe and cost-effective for smoking cessation among adult smokers?
- Study Type Included
- Inclusion criteria: Phase III Randomized controlled trials among adult (aged 18 and over) smokers that compare cytisine to placebo, standard care or other smoking cessation intervention. Studies published in English language. Exclusion criteria: 1) studies where the focus is not on smoking cessation; 2) studies where cytisine is part of a multi-modality intervention
- Condition Being Studied
- Smoking is a major cause of morbidity and mortality worldwide. Five million adults in Canada are cigarette smokers. Smoking cessation is beneficial for long term health, but many smokers make several quit attempts before success is achieved. Cytisine is a cheap natural plant-based product that may help smokers quit. This review focuses on determining its efficacy, safety and cost effectiveness.
- Participant
- Adult smokers (aged 18 and over)
- Animal
- Human Disease Modelled
- Intervention
- Cytisine at any dose or duration of treatment.
- Comparator Control
- Placebo, standard care (as defined in the individual studies), other smoking cessation interventions (behavioral therapy, nicotine replacement therapy, varenicline or bupropion)
- Main Outcome
- Biochemically verified continuous abstinence at 6 months.
- Outcome Measure
- Additional Outcome
- 1) Biochemically verified continuous abstinence at 6 months, 2) self-reported abstinence from smoking at 1 month, 6 and 12 months; 3) 7-day point prevalence abstinence from smoking at 1, 6 and 12 months
- Study Method
- Cost effectiveness, Intervention, Meta-analysis, Systematic review
- Keyword
- Alkaloids; Cost-Benefit Analysis; Humans; Quinolizines; Smoking Cessation; cytisine
- Contact
- SANDRA OFORI [email protected]
- Organisational Affiliation
- McMaster University
- Funding Source
- None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> Not applicable
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Canada
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-07-07
- Registration Date
- 2021-08-06
- Anticipated Start Date
- 2021-08-15
- Anticipated Completion Date
- 2022-07-29
- Title Cn
- 金雀花碱用于戒烟的有效性、安全性和成本效果：系统评价与Meta分析
- Title En
- The efficacy, safety and cost effectiveness of Cytisine for smoking cessation: a systematic review and meta-analysis
- Bilingual Status
- complete