Meta AnalysisID 208
植物油对代谢紊乱患者代谢状况的比较有效性：随机对照临床试验的网状Meta分析
CRD42022323171
We aim to evaluate and rank the effects of commonly use edible vegetable oils (sunflower oil, corn oil, soybean oil, sesame oil, flaxseed oil, canola oil, safflower oil, cottonseed oil, olive oil, avocado oil, peanut oil
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Record Fields
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- Meta Analysis Id
- 208
- Evidence Id
- 8766
- Core Evidence Id
- 8766
- Source Meta Analysis Id
- 192
- Herb2 Meta Analysis Id
- HBMA000192
- Crd Id
- CRD42022323171
- Title
- Comparative effectiveness of vegetable oils on metabolic status in patients with metabolic disorders: a network meta-analysis of randomized controlled clinical trials
- Review Question
- We aim to evaluate and rank the effects of commonly use edible vegetable oils (sunflower oil, corn oil, soybean oil, sesame oil, flaxseed oil, canola oil, safflower oil, cottonseed oil, olive oil, avocado oil, peanut oil) on improving metabolic status (abdomen circumference, blood pressure, low density lipoprotein cholesterol (LDL-C) , high density lipoprotein cholesterol (HDL-C), total cholesterol (TC), triglyceride (TG), fasting glucose, glycosylated hemoglobin) in patients with metabolic disorders.
- Study Type Included
- Randomized controlled trial
- Condition Being Studied
- In the 2015-2020 dietary guidelines for Americans, foods rich in unsaturated fatty acid are recommended to replace those containing saturated fatty acid, which aims to reduce the risk of cardiovascular diseases events (CVD) and CVD-related deaths. Metabolic disorders, including waist obesity, hypertension, dyslipidemia and hyperglycemia, are risk factors of CVD. Therefore, for patients with metabolic disorders, a healthy eating pattern is as important as drug therapy. Vegetable oils are one of main sources of unsaturated fatty acid in our daily life. However, there are various of edible vegetable oils from different regions and countries, and the beneficial effects of those agents on improving metabolic status such as regulating blood pressure, blood lipids and glucose are inconsistent. Up to now, no research has been done to compare the effects of different vegetable oils on metabolic status in patients with metabolic disorders.
- Participant
- Patients with metabolic disorders: I. Central obesity; II. Hyperlipidemia: 1)Hypertriglyceridemia: triglycerides ≥1·7 mmol/L; or 2) Low HDL cholesterol: <1·0 mmol/L (male), <1·3 mmol/L (female); or 3) Medication III. Hypertension: blood pressure ≥135/85 mm Hg or medication IV. Fasting plasma glucose ≥6·1 mmol/L or T2DM or Medication
- Animal
- Human Disease Modelled
- Intervention
- Interventions: sunflower oil, corn oil, soybean oil, sesame oil, flaxseed oil, canola oil, safflower oil, cottonseed oil, olive oil, avocado oil, peanut oil;
- Comparator Control
- Comparison: placebo, a restricted-calorie diet, lifestyle intervention and standard diets according to dietary guidelines.
- Main Outcome
- Abdomen circumference, blood pressure, HDL-C, TG, fasting glucose
- Outcome Measure
- Additional Outcome
- LDL-C, TC, glycosylated hemoglobin
- Study Method
- Intervention, Network meta-analysis, Systematic review
- Keyword
- Humans; Metabolic Diseases; Network Meta-Analysis; Plant Oils
- Contact
- Yuxiang Long [email protected]
- Organisational Affiliation
- Chongqing Medical University
- Funding Source
- None.
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-04-04
- Registration Date
- 2022-05-05
- Anticipated Start Date
- 2022-04-01
- Anticipated Completion Date
- 2022-10-01
- Title Cn
- 植物油对代谢紊乱患者代谢状况的比较有效性：随机对照临床试验的网状Meta分析
- Title En
- Comparative effectiveness of vegetable oils on metabolic status in patients with metabolic disorders: a network meta-analysis of randomized controlled clinical trials
- Bilingual Status
- complete